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Stimuli-Responsive Nanocomposite Hydrogels for Oral Diseases.
Conte, Raffaele; Valentino, Anna; Romano, Silvia; Margarucci, Sabrina; Petillo, Orsolina; Calarco, Anna.
Afiliación
  • Conte R; Research Institute on Terrestrial Ecosystems (IRET), National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.
  • Valentino A; National Biodiversity Future Center (NBFC), 90133 Palermo, Italy.
  • Romano S; Research Institute on Terrestrial Ecosystems (IRET), National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.
  • Margarucci S; National Biodiversity Future Center (NBFC), 90133 Palermo, Italy.
  • Petillo O; Research Institute on Terrestrial Ecosystems (IRET), National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.
  • Calarco A; Research Institute on Terrestrial Ecosystems (IRET), National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.
Gels ; 10(7)2024 Jul 18.
Article en En | MEDLINE | ID: mdl-39057501
ABSTRACT
Oral diseases encompassing conditions such as oral cancer, periodontitis, and endodontic infections pose significant challenges due to the oral cavity's susceptibility to pathogenic bacteria and infectious agents. Saliva, a key component of the oral environment, can compromise drug efficacy during oral disease treatment by diluting drug formulations and reducing drug-site interactions. Thus, it is imperative to develop effective drug delivery methods. Stimuli-responsive nanocomposite hydrogels offer a promising solution by adapting to changes in environmental conditions during disease states, thereby enabling targeted drug delivery. These smart drug delivery systems have the potential to enhance drug efficacy, minimize adverse reactions, reduce administration frequency, and improve patient compliance, thus facilitating a faster recovery. This review explores various types of stimuli-responsive nanocomposite hydrogels tailored for smart drug delivery, with a specific focus on their applications in managing oral diseases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Gels Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Gels Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza