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Unveiling the Rarity: A Case of a Mixed Neuroendocrine-Non-Neuroendocrine Tumor of the Gastroesophageal Junction.
Alamin, Faris; Sage, Hannah; Torres, Isabel; Parikh, Jignesh; Zayat, Vania.
Afiliación
  • Alamin F; Internal Medicine, University of Central Florida/HCA Osceola Hospital, Orlando, USA.
  • Sage H; Pathology, University of Central Florida College of Medicine, Orlando, USA.
  • Torres I; Pathology, University of Central Florida College of Medicine, Orlando, USA.
  • Parikh J; Pathology, Orlando Veterans Affairs Medical Center, Orlando, USA.
  • Zayat V; Pathology, Orlando Veterans Affairs Medical Center, Orlando, USA.
Cureus ; 16(6): e63141, 2024 Jun.
Article en En | MEDLINE | ID: mdl-39055477
ABSTRACT
Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are a rare group of heterogeneous tumors, consisting of an endocrine and a nonendocrine component, which can develop throughout the gastrointestinal (GI) tract. This case presents a 70-year-old man with a complex medical history who initially presented with an upper GI bleed. After being stabilized, he underwent an esophagogastroduodenoscopy (EGD) that revealed a suspicious gastroesophageal junction (GEJ) mass. Histopathological studies paired with immunohistochemical investigations of the mass confirmed the rare diagnosis of MiNENs. He then underwent an endoscopic submucosal dissection (ESD) with subsequent chemotherapy and adjunct radiotherapy, with no recurrence noted on post-treatment surveillance. This case highlights the need for an EGD, histopathological examination, and immunohistochemical staining for detecting the underlying etiology of an upper GI bleed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos