Your browser doesn't support javascript.
loading
A randomized prospective study comparing the effect of low-volume bowel preparations for colonoscopy preparation in China.
Shen, Jianwei; Sheng, Hong; He, Hui; Sun, Changbo; Han, Xufeng; Zhu, Xianjie; Wang, Chunwei; Shen, Ruiwei; Ye, Qunqun; Yuan, Xiaogang; Zhao, Qiang; Yang, Nuonan; Wang, Jiaqi; Lu, Ting; Chen, Dahua; Chen, Dawei; Lin, Jieqiong; Shao, Xiaona.
Afiliación
  • Shen J; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Sheng H; Department of Gastroenterology, Xiangshan County First People's Hospital Medical Health Group, Ningbo, Zhejiang, China.
  • He H; Department of Gastroenterology, Ningbo Yinzhou Anorectal Hospital Co., Ltd, Ningbo, Zhejiang, China.
  • Sun C; Department of Gastroenterology, Ningbo Municipal Hospital of TCM, Ningbo, Zhejiang, China.
  • Han X; Second Department of Internal Medicine, Yuyao Hospital of TCM, Ningbo, Zhejiang, China.
  • Zhu X; Department of Gastroenterology, Ninghai County Hospital of Traditional Chinese Medicine, Ningbo, Zhejiang, China.
  • Wang C; Health Science Center, Ningbo University, Ningbo, Zhejiang, China.
  • Shen R; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Ye Q; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Yuan X; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Zhao Q; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Yang N; Health Science Center, Ningbo University, Ningbo, Zhejiang, China.
  • Wang J; Health Science Center, Ningbo University, Ningbo, Zhejiang, China.
  • Lu T; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Chen D; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Chen D; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Lin J; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
  • Shao X; Department of Gastroenterology, Ningbo Medical Center Li Huili Hospital, Ningbo, Zhejiang, China.
Scand J Gastroenterol ; 59(9): 1112-1119, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39054602
ABSTRACT

AIM:

To evaluate the effect of sodium picosulfate/magnesium citrate (SPMC) and 3 L split-dose polyethylene glycol (PEG) with or without dimethicone on bowel preparation before colonoscopy.

METHODS:

In this multicenter, prospective, randomized, controlled study conducted from April 2021 to December 2021, consecutive adult patients scheduled for colonoscopy were prospectively randomized into four groups SPMC, SPMC plus dimethicone, 3 L PEG, and 3 L PEG plus dimethicone. Primary endpoint was colon cleansing based on Boston Bowel Preparation Scale (BBPS). Secondary endpoints were bubble score, time to cecal intubation, adenoma detection rate (ADR), patient safety and compliance, and adverse events.

RESULTS:

We enrolled 223 and 291 patients in SPMC and 3 L PEG group, respectively. The proportion with acceptable bowel cleansing, total BBPS score and cecal intubation time were similar in all four subgroups (p > 0.05). Patient-reported acceptability and tolerability was significantly greater in SPMC than 3 L PEG group (p < 0.001); adverse events were significantly lower in SPMC than latter group (p < 0.001). ADR in both groups was greater than 30%.

CONCLUSION:

SPMC had significantly higher acceptability and tolerability than 3 L PEG, however, was similar in terms of bowel-cleansing effect and cecal intubation time and hence can be used before colonoscopy preparation.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Organometálicos / Picolinas / Polietilenglicoles / Catárticos / Colonoscopía / Citratos Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Scand J Gastroenterol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Organometálicos / Picolinas / Polietilenglicoles / Catárticos / Colonoscopía / Citratos Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Scand J Gastroenterol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido