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Enhanced Recovery After Surgery 2.0: Optimizing Pain Management in Nuss Procedure: Cryoablation and Nerve Block Strategies for Reduced Opioid Use.
Wharton, Kristin; Chidiac, Charbel; Lopez, Carla; Hunsberger, Joann; Rhee, Daniel; Cappiello, Clint; Garcia, Alejandro V.
Afiliación
  • Wharton K; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Chidiac C; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Lopez C; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Hunsberger J; Department of Anesthesiology & Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Rhee D; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Cappiello C; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Garcia AV; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: agarci41@jhmi.edu.
J Surg Res ; 301: 563-571, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39053171
ABSTRACT

INTRODUCTION:

Our study assesses the association between cryoablation, with and without nerve block supplementation, post-Nuss procedure pain, and opioid use in pectus excavatum (PE) patients.

METHODS:

We conducted a retrospective cohort study at a single center for PE patients who underwent the Nuss procedure from 2017 to 2022. Outcomes included postoperative opioid use (measured in oral morphine milligram equivalent per kilogram [OME/kg]), average pain score (scale 0-10), and length of stay (LOS).

RESULTS:

One hundred sixty-four patients (146 males and 18 females) were included, with 79 (48.2%) receiving neither cryoablation nor nerve block, 60 (36.6%) receiving intraoperative cryoablation alone, and 25 (15.2%) receiving both cryoablation and nerve block. The median age was 16 y. Nerve block recipients consumed fewer opioids during hospitalization than cryoablation alone and nonintervention groups (1.5 versus 2.3 versus 5.8 OME/kg, respectively, P < 0.0001). Average pain scores over the total LOS were lower in nerve block recipients (3.5 versus 3.8 versus 4.2, P = 0.03), particularly on postoperative day 0 (P = 0.002). Nerve block recipients had a shorter LOS than cryoablation alone and nonintervention groups (43.4 versus 54.7 versus 66.2 h, P < 0.0001). On multivariate analysis, cryoablation alone resulted in significantly less opioid use compared to no intervention (3.32 OME/kg reduction, 95% confidence interval -4.16 to -2.47, P < 0.0001). Addition of nerve block further reduced opioid use by 1.10 OME/kg (95% confidence interval -2.07 to -0.14, P = 0.04).

CONCLUSIONS:

Cryoablation with nerve block supplementation is associated with reduced pain, opioid use, and LOS post-Nuss for PE repair compared to cases without cryoablation or with cryoablation only. Cryoablation with regional nerve blocks should be considered for Nuss repair under the enhanced recovery after surgery pathway.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Criocirugía / Manejo del Dolor / Tórax en Embudo / Recuperación Mejorada Después de la Cirugía / Analgésicos Opioides / Tiempo de Internación / Bloqueo Nervioso Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: J Surg Res Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Criocirugía / Manejo del Dolor / Tórax en Embudo / Recuperación Mejorada Después de la Cirugía / Analgésicos Opioides / Tiempo de Internación / Bloqueo Nervioso Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: J Surg Res Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos