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Decomposing the association of psychosocial wellbeing with all-cause mortality: the mediating role of physical health and lifestyle factors.
Alimujiang, Aliya; Strecher, Victor; McLean, Karen; Mondul, Alison M; Pearce, Celeste Leigh; Mukherjee, Bhramar.
Afiliación
  • Alimujiang A; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Strecher V; Kumanu, Ann Arbor, MI, USA.
  • McLean K; Department of Health Behavior & Health Education, Director for Innovation and Social Entrepreneurship, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Mondul AM; Department of Health Behavior & Health Education, Director for Innovation and Social Entrepreneurship, University of Michigan School of Public Health, Ann Arbor, MI, USA.
  • Pearce CL; Department of Obstetrics and Gynecology, University of Michigan Health System, Ann Arbor, MI, USA.
  • Mukherjee B; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Article en En | MEDLINE | ID: mdl-39044017
ABSTRACT

PURPOSE:

This study quantified the effect of 48 psychosocial constructs on all-cause mortality using data from 7,698 individuals in the U.S. Health and Retirement Study.

METHODS:

Latent class analysis was used to divide participants into mutually exclusive psychosocial wellbeing groups (good, average, or poor) which was subsequently considered as the exposure. Mediation analysis was then conducted to determine the direct effect of the psychosocial wellbeing groups and the indirect (mediating) effects of physical health (functional status and comorbid conditions) and lifestyle factors (physical activity, smoking, and alcohol consumption) on overall survival. We also created a composite health index measure representing the summative effect of the mediators.

RESULTS:

We observed a strong and statistically significant total effect (TE) between survival time and psychosocial wellbeing group (survival time ratio (SR) = 1.73, 95% confidence interval (CI)1.50,2.01 when comparing good to poor). Mediation analysis revealed that the direct effect via psychosocial wellbeing group accounted for more than half of the TE (SR = 1.46, 95% CI1.27,1.67). The composite health index measure mediated 36.2% of the TE with the natural indirect effect SR of 1.18 (95% CI1.13,1.22).

CONCLUSION:

Our findings demonstrate the interconnectedness between psychosocial wellbeing and physical health and lifestyle factors on survival.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Soc Psychiatry Psychiatr Epidemiol Asunto de la revista: CIENCIAS SOCIAIS / EPIDEMIOLOGIA / PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Soc Psychiatry Psychiatr Epidemiol Asunto de la revista: CIENCIAS SOCIAIS / EPIDEMIOLOGIA / PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania