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Analysis and comparison of blood metabolome of forest musk deer in musk secretion and non-secretion periods.
Wang, Yufan; Yang, Pengcheng; Chen, Taoyue; Hu, Jingyao; An, Xian; Yao, Congxue; Xu, Liancheng; Xu, Yuli; Liu, Shuqiang.
Afiliación
  • Wang Y; School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, China.
  • Yang P; School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, China.
  • Chen T; School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, China.
  • Hu J; School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, China.
  • An X; School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, China.
  • Yao C; Yanshe Biological Technology Co., Ltd, Shanghai, China.
  • Xu L; Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd, Fujian, China.
  • Xu Y; Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd, Fujian, China.
  • Liu S; School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, China. liushuqiang@bjfu.edu.cn.
Sci Rep ; 14(1): 16980, 2024 07 23.
Article en En | MEDLINE | ID: mdl-39043795
ABSTRACT
Musk is an important animal product, but the musk secretion mechanism of forest musk deer (Moschus berezovskii) is still unclear. The musk synthesis process in forest musk deer is extremely complex, and many raw materials are directly or indirectly derived from forest musk deer blood. In this study, metabolomics was used to analyze the blood of forest musk deer in secretory and non-secretory phases for the first time, aim at explaining the secretion mechanism from the perspective of blood metabolism. We found that P450-related, choline-related, axonal regeneration and other pathways and related metabolites were significantly enriched during the musk secretion of forest musk deer. These pathways and metabolites related to P450 and choline in blood may have important implications for the mechanism of musk secretion in forest musk deer, because blood components were closely related to musk components and could provide raw materials for musk synthesis in musk gland cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ciervos / Ácidos Grasos Monoinsaturados / Metaboloma Límite: Animals Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ciervos / Ácidos Grasos Monoinsaturados / Metaboloma Límite: Animals Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido