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Evaluation of Antioxidant and Antimicrobial Activity of Ethanolic Extract of Medicinal Plants Baccaurea Ramiflora and Microcos Paniculata.
Saha, Suvendu; Gouda, T Shivaraj; Mallik, Arunabha.
Afiliación
  • Saha S; Associate Professor, Department of Pharmacology, Marri Laxman Reddy Institute of Pharmacy, Dundigal, Hyderabad-500043, Telangana, India.
  • Gouda TS; Department of Pharmacology, NET Pharmacy College, Raichur, India.
  • Mallik A; Professor, Department of Pharmacology, Marri Laxman Reddy Institute of Pharmacy, Dundigal, Hyderabad-500043, Telangana, India.
Zhongguo Ying Yong Sheng Li Xue Za Zhi ; 40: e20240014, 2024 Jul 24.
Article en En | MEDLINE | ID: mdl-39043470
ABSTRACT

OBJECTIVE:

The present study was undertaken to investigate the antioxidant and antimicrobial effect of ethanolic leaf extract of Baccaurea ramiflora and Microcos paniculata.

METHODS:

DPPH radical scavenging activity, Nitric oxide scavenging activity, Super oxide anion radical scavenging activity, Reducing power assay were used to assess antioxidant efficacy. Zone of Inhibition determination by Agar well diffusion assay was used to assess antimicrobial activity.

RESULTS:

The Baccaurea ramiflora and Microcos paniculata leaves extracted with different solvents such as petroleum ether, chloroform, ethanol and water among that in leaves ethanolic extract produce 10.78, 10.38 percentage yield respectively. Both the extracts subjected for phytochemical investigation revealed the presence of alkaloids, glycosides, tannins, saponins, proteins and flavonoids. Ethanolic extract of Baccaurea ramiflora showed maximum inhibition zone diameter was obtained in Salmonella typhi (Gram-negative bacteria) with diameter 29 mm and 25 mm respectively at 200mg/ml and 100mg/ml. Similarly, Ethanolic extract of Microcos paniculata showed minimum inhibition zone diameter compare to Baccaurea ramiflora was obtained in Salmonella typhi (Gram-negative bacteria) with diameter 23 mm and 19 mm respectively at 200mg/ml and 100mg/ml. Ethanolic extract of Baccaurea ramiflora showed maximum inhibition zone diameter was obtained in Aspergillus fumigates with diameter 25 mm and 22 mm respectively at 200mg/ml and 100mg/ml. Similarly, Ethanolic extract of Microcos paniculata showed minimum inhibition zone diameter compare to Baccaurea ramiflora was obtained in Aspergillus fumigates with diameter 21 mm and 19 mm respectively at 200mg/ml and 100mg/ml.

CONCLUSION:

The current findings point to Baccaurea ramiflora and Microcos paniculata antioxidant and antimicrobial properties. However future studies should be designed to isolate the active constituents responsible for the specified effect.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plantas Medicinales / Extractos Vegetales / Antiinfecciosos / Antioxidantes Idioma: En Revista: Zhongguo Ying Yong Sheng Li Xue Za Zhi Asunto de la revista: FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plantas Medicinales / Extractos Vegetales / Antiinfecciosos / Antioxidantes Idioma: En Revista: Zhongguo Ying Yong Sheng Li Xue Za Zhi Asunto de la revista: FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: China