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Low-cost heat assisted ambient ionization source for mass spectrometry in food and pharmaceutical screening.
Gazeli, Odhisea; Elia, Efstathios A; Argirusis, Nikolaos; Lazarou, Constantinos; Anastassiou, Charalambos; Franzke, Joachim; Garcia-Reyes, Juan F; Georghiou, George E; Agapiou, Agapios.
Afiliación
  • Gazeli O; PHAETHON Centre of Excellence for Intelligent, Efficient and Sustainable Energy Solutions, Nicosia 2109, Cyprus.
  • Elia EA; ENAL Electromagnetics and Novel Applications Lab, Department of Electrical and Computer Engineering, University of Cyprus, Nicosia 2109, Cyprus.
  • Argirusis N; Analytical Chemistry Research Group, Department of Physical and Analytical Chemistry, University of Jaén, 23071 Jaén, Spain.
  • Lazarou C; Department of Chemistry, University of Cyprus, P.O. Box 20537, Nicosia, 1678, Cyprus. elia.efstathios-andreas@ucy.ac.cy.
  • Anastassiou C; 4mat4nrg GmbH, 38678 Clausthal-Zellerfeld, Germany.
  • Franzke J; PHAETHON Centre of Excellence for Intelligent, Efficient and Sustainable Energy Solutions, Nicosia 2109, Cyprus.
  • Garcia-Reyes JF; ENAL Electromagnetics and Novel Applications Lab, Department of Electrical and Computer Engineering, University of Cyprus, Nicosia 2109, Cyprus.
  • Georghiou GE; PHAETHON Centre of Excellence for Intelligent, Efficient and Sustainable Energy Solutions, Nicosia 2109, Cyprus.
  • Agapiou A; ENAL Electromagnetics and Novel Applications Lab, Department of Electrical and Computer Engineering, University of Cyprus, Nicosia 2109, Cyprus.
Analyst ; 149(17): 4487-4495, 2024 Aug 19.
Article en En | MEDLINE | ID: mdl-39042100
ABSTRACT
Ambient Ionization Mass Spectrometry (AI-MS) techniques have revolutionized analytical chemistry by enabling rapid analysis of samples under atmospheric conditions with minimal to no preparation. In this study, the optimization of a cold atmospheric plasma for the analysis of food and pharmaceutical samples, liquid and solid, using a Heat-Assisted Dielectric Barrier Discharge Ionization (HA-DBDI) source is described. A significant enhancement in analyte signals was observed when a heating element was introduced into the design, potentially allowing for greater sensitivity. Furthermore, the synergy between the inlet temperature of the mass spectrometer and the heating element allows for precise control over the analytical process, leading to improved detection sensitivity and selectivity. Incorporating computational fluid dynamic (CFD) simulations into the study elucidated how heating modifications can influence gas transport properties, thereby facilitating enhanced analyte detection and increased signal intensity. These findings advance the understanding of HA-DBDI technology and provide valuable insights for optimizing AI-MS methodologies for a wide range of applications in food and pharmaceutical analysis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Análisis de los Alimentos / Calor Idioma: En Revista: Analyst Año: 2024 Tipo del documento: Article País de afiliación: Chipre Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Análisis de los Alimentos / Calor Idioma: En Revista: Analyst Año: 2024 Tipo del documento: Article País de afiliación: Chipre Pais de publicación: Reino Unido