Potential diagnostic, prognostic, and predictive biomarkers of gastric cancer.
Health Sci Rep
; 7(7): e2261, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-39040881
ABSTRACT
Background:
Gastric cancer (GC), a malignant epithelial tumor, is the fourth leading cause of cancer-related death worldwide. Therapeutic strategies for GC, despite the biggest challenges, can significantly improve survival rates through early detection and effective screening methods.Aim:
To provide brief information on the necessity of multiple specific diagnostic, prognostic, and predictive markers for GC.Methods:
This review was conducted using a variety of search engines, including PubMed Central, Scopus, Web of Science, Google Scholar, and others.Results:
Some potential biomarkers that provide essential information include circulating tumor cells (CTCs), DNA methylation, claudin 18.2, fibroblast growth factor receptor 2 (FGFR2), long noncoding RNAs (lncRNAs), cell-free DNA (cfDNA), microRNAs, and serum pepsinogens.Conclusion:
Multiple tumor markers are essential for screening, tumor identification, staging, prognostic assessment, and monitoring recurrence after therapy due to the absence of a single tumor indicator for diagnosing, prognosticating, and predicting GC.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Health Sci Rep
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos