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Predictive accuracy of wideband absorbance in children with large vestibular aqueduct syndrome: A single-center retrospective study.
Jiang, Wen; Li, Xuanyi; Mu, Yi; Zhang, Huiying; Konduru, Naveena; Qiao, Yuehua; Zhao, Fei; Liu, Wen.
Afiliación
  • Jiang W; Department of Otolaryngology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, China.
  • Li X; The Second College of Clinical Medicine, Xuzhou Medical University, Xuzhou, 221000, China.
  • Mu Y; Auditory Engineering Laboratory of Jiangsu Province, Xuzhou, 221000, China.
  • Zhang H; The College of Medical Technology, Xuzhou Medical University, Xuzhou, 221000, China.
  • Konduru N; Department of Otolaryngology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, China.
  • Qiao Y; The College of Medical Technology, Xuzhou Medical University, Xuzhou, 221000, China.
  • Zhao F; The College of Medical Technology, Xuzhou Medical University, Xuzhou, 221000, China.
  • Liu W; Department of Otolaryngology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, China.
Heliyon ; 10(13): e33776, 2024 Jul 15.
Article en En | MEDLINE | ID: mdl-39040356
ABSTRACT

Objectives:

This study aimed to assess the clinical significance of Wideband Absorbance (WBA) in children with Large Vestibular Aqueduct Syndrome (LVAS), which could potentially serve as diagnostic and predictive markers for LVAS in children.

Design:

This was a single-center retrospective case-control study. Audiological measurements and Wideband Acoustic Immittance (WAI) were performed. Propensity score matching (PSM) was considered to treat group imbalance. The Receiver Operating Characteristic (ROC) curves and area under the ROC curve (AUC) were used to evaluate the sensitivity and specificity of WBA. Study sample Participants included 42 children with LVAS and 163 normal children aged 6 months -11 years recruited from clinical audiology settings between 2019 and 2021.

Results:

The WBA at Tympanometric Peak Pressure (WBATPP) and Ambient Pressure (WBAA) in the LVAS group were significantly lower than those of the control group at 1259-2000 Hz but higher at 4000-6349 Hz (p < 0.05, power >0.8). The WBAA (1587 Hz) AUC value was 0.805, identifying a score ≤0.565 as indicative of a LVAS risk.

Conclusions:

WBA holds promise in distinguishing LVAS from the normal condition and warrants further exploration as a tool to examine the influence of inner ear pressure on acoustic energy transmission in the middle ear.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido