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Hysteroscopic Endometrial Fundal Incision versus Hysteroscopy Only in Oocyte Recipients: A Randomized Controlled Trial Assessing The Reproductive Outcomes.
Peitsidis, Nikolaos; Tsakiridis, Ioannis; Najdecki, Robert; Michos, Georgios; Kalogiannidis, Ioannis; Athanasiadis, Apostolos; Papanikolaou, Evangelos.
Afiliación
  • Peitsidis N; Assisting Nature Centre of Reproduction and Genetics, Thessaloniki, Greece.
  • Tsakiridis I; Assisting Nature Centre of Reproduction and Genetics, Thessaloniki, Greece. Email: igtsakir@auth.gr.
  • Najdecki R; Third Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Michos G; Assisting Nature Centre of Reproduction and Genetics, Thessaloniki, Greece.
  • Kalogiannidis I; Assisting Nature Centre of Reproduction and Genetics, Thessaloniki, Greece.
  • Athanasiadis A; Third Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Papanikolaou E; Third Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Int J Fertil Steril ; 18(Suppl 1): 3-9, 2024 Jul 13.
Article en En | MEDLINE | ID: mdl-39033364
ABSTRACT

BACKGROUND:

Endometrial scratching (ES) remains controversial regarding its potential effectiveness in improving pregnancy rates. The objective of the present study was to assess the impact of endometrial fundal incision (EFI) during hysteroscopy on reproductive outcomes in a population of oocyte recipients. MATERIALS AND

METHODS:

A randomized controlled trial was conducted between 2020 and 2023 at the Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki and "Assisting Nature Centre of Reproduction and Genetics". The study population consisted of women who underwent hysteroscopy randomly assigned in a 11 ratio to either EFI (one to three months before embryotransfer with donor oocytes) or no intervention throughout office hysteroscopy. Clinical pregnancy and live birth rates were the primary outcomes.

RESULTS:

After the exclusion of patients with intraoperative diagnosed endometrial pathology, a total of 124 women underwent randomization. The pregnancy test was positive in 79% (n=49/62) of the women in the EFI compared to 59.7% (n=37/62) in the hysteroscopy-only group (P=0.019), while the live birth rates did not differ between the two groups (58.1%, n=36/62 vs. 51.6%, n=32/62, P=0.470).

CONCLUSION:

EFI during hysteroscopy seems to improve pregnancy rates in oocyte recipients without intrauterine pathology, while live birth rates are not affected by the EFI. These results should be interpreted with caution before the implementation of EFI in the routine in vitro fertilization (IVF) practice (registration number NCT04580056).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Fertil Steril Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Irán
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Fertil Steril Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Irán