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Humanistic and Economic Burden of Atopic Dermatitis in Pediatric Patients in Spain: A Systematic Review.
Torrelo Fernández, A; Vicente, A; Martin-Santiago, A; de Lucas Laguna, R; Armario-Hita, J C; Moro, R; Díaz-Cerezo, S; Lizán, L; Núñez, M.
Afiliación
  • Torrelo Fernández A; Servicio de Dermatología, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
  • Vicente A; Servicio de Dermatología, Hospital Sant Joan de Deu Barcelona, Universidad de Barcelona, Esplugues de Llobregat, Barcelona, Spain.
  • Martin-Santiago A; Servicio de Dermatología, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, Spain.
  • de Lucas Laguna R; Servicio de Dermatología, Hospital Universitario La Paz, Madrid, Spain.
  • Armario-Hita JC; Servicio de Dermatología, Hospital Punta de Europa, Algeciras, Universidad de Cádiz, Cádiz, Spain.
  • Moro R; Eli Lilly and Company, Madrid, Spain.
  • Díaz-Cerezo S; Eli Lilly and Company, Madrid, Spain.
  • Lizán L; Outcomes'10, S.L., Castellón de la Plana, Spain; Departamento de Medicina, Universidad Jaume I, Castellón de la Plana, Spain.
  • Núñez M; Eli Lilly and Company, Madrid, Spain. Electronic address: nunez_mercedes@lilly.com.
Actas Dermosifiliogr ; 2024 Jul 18.
Article en En, Es | MEDLINE | ID: mdl-39032775
ABSTRACT
Atopic dermatitis (AD) is a chronic, inflammatory skin disease affecting all age groups, particularly children. This systematic review provides an overview of the humanistic and economic disease burden in the pediatric population with AD in Spain. The evidence, collected from 11 observational studies published over the past 10 years, exhibits the most common characteristics of the patients, disease burden, patient-reported outcomes, use of resources, and treatment patterns. The burden of AD extends beyond physical symptoms, with associated comorbidities such as asthma and impaired health-related quality of life and mental health disorders, particularly in severe cases. Traditional therapies, primarily topical corticosteroids, face adherence and efficacy challenges. Despite promising innovative treatments and available biological therapies, their use is still limited in the pediatric population. The findings of the present review highlight the scarce scientific evidence on the economic burden of pediatric AD, as well as the most updated humanistic evidence on this disease. At the same time, the need for individualized care and innovative therapeutic interventions to address the multifaceted challenges of pediatric AD in Spain is evident.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En / Es Revista: Actas Dermosifiliogr Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: España

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En / Es Revista: Actas Dermosifiliogr Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: España