Your browser doesn't support javascript.
loading
Growth and Cognitive Development in Tanzanian Children are Associated with Timing of Birth in Relation to Seasonal Malnutrition.
Parpia, Tarina; Elwood, Sarah; Rogawski McQuade, Elizabeth T; Svensen, Erling; Wanjuhi, Anne; Jatosh, Samwel; Bayo, Eliwaza; Hhando, Emanuel; Houpt, Eric R; Mduma, Estomih; DeBoer, Mark D; Scharf, Rebecca J; Platts-Mills, James A.
Afiliación
  • Parpia T; Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA.
  • Elwood S; Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA.
  • Rogawski McQuade ET; Department of Epidemiology, Emory University, Atlanta, GA.
  • Svensen E; Haukeland University Hospital, Bergen, Norway.
  • Wanjuhi A; Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA.
  • Jatosh S; Haydom Global Health Research Centre, Haydom, Tanzania.
  • Bayo E; Haydom Global Health Research Centre, Haydom, Tanzania.
  • Hhando E; Haydom Global Health Research Centre, Haydom, Tanzania.
  • Houpt ER; Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA.
  • Mduma E; Haydom Global Health Research Centre, Haydom, Tanzania.
  • DeBoer MD; Department of Pediatrics, University of Virginia, Charlottesville, VA.
  • Scharf RJ; Department of Pediatrics, University of Virginia, Charlottesville, VA.
  • Platts-Mills JA; Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA. Electronic address: jp5t@virginia.edu.
J Pediatr ; 275: 114202, 2024 Jul 19.
Article en En | MEDLINE | ID: mdl-39032770
ABSTRACT

OBJECTIVE:

To evaluate in a rural Tanzanian birth cohort the association between birth timing in relation to the preharvest lean season and early-life growth and cognitive development. STUDY

DESIGN:

Children were enrolled within 14 days of birth and followed up for 18 months. Child anthropometry was measured every 3 months. The Malawi Developmental Assessment Test was administered at the end of follow-up. We estimated the association between timing of birth in the context of other early childhood risk factors and both growth and Malawi Developmental Assessment Test scores.

RESULTS:

Children born in the preharvest months September and October had the lowest cognitive scores at 18 months, compared with birth in July and August (-1.05 change in overall Malawi Developmental Assessment Test development-for-age Z score, 95% CI -1.23, -0.86). This association was observed for the language (-1.67 change in development-for-age Z score; 95% CI -1.93, -1.40) and fine motor subcomponent scores (-1.67; 95% CI -1.96, -1.38) but not for gross motor (-0.07; 95% CI -0.23, 0.10) or social subcomponents (-0.07; 95% CI -0.23, 0.10). Children born in September and October were the longest at birth but had the largest declines in growth Z scores during the first 6 months.

CONCLUSIONS:

There was a strong association between birth at the beginning of the preharvest season and poor growth and cognitive development. If these associations were mediated by the preharvest postnatal environment, targeted maternal and child interventions for children born during high-risk periods may improve these outcomes. TRIAL REGISTRATION NCT03268902 (https//clinicaltrials.gov/study/NCT03268902).
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pediatr Año: 2024 Tipo del documento: Article País de afiliación: Ciudad del Vaticano Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pediatr Año: 2024 Tipo del documento: Article País de afiliación: Ciudad del Vaticano Pais de publicación: Estados Unidos