Your browser doesn't support javascript.
loading
Label-free assessment of the transformation zone using multispectral diffuse optical imaging toward early detection of cervical cancer.
Karthika, J; Anantharaju, Arpitha; Koodi, Dhanush; Pandya, Hardik J; Pal, Uttam M.
Afiliación
  • Karthika J; Department of Sciences and Humanities, Indian Institute of Information Technology, Design and Manufacturing, Kancheepuram, Chennai, Tamil Nadu, India.
  • Anantharaju A; Department of Gynecology and Obstetrics, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, Puducherry, India.
  • Koodi D; Department of Electronics and Communication Engineering, Sri Sairam Engineering College, Chennai, Tamil Nadu, India.
  • Pandya HJ; Department of Electronic Systems Engineering, Indian Institute of Science, Bangalore, Karnataka, India.
  • Pal UM; Department of Electronics and Communications, Indian Institute of Information Technology, Design and Manufacturing, Kancheepuram, Chennai, Tamil Nadu, India.
J Biophotonics ; : e202400114, 2024 Jul 20.
Article en En | MEDLINE | ID: mdl-39032125
ABSTRACT
The assessment of the transformation zone is a critical step toward diagnosis of cervical cancer. This work involves the development of a portable, label-free transvaginal multispectral diffuse optical imaging (MDOI) imaging probe to estimate the transformation zone. The images were acquired from N = 5 (N = 1 normal, N = 2 premalignant, and N = 2 malignant) patients. Key parameters such as spectral contrast ratio (ρ) at 545 and 450 nm were higher in premalignant (0.29, 0.25 for 450 nm and 0.30, 0.17 for 545 nm) as compared to the normal patients (0.13 and 0.14 for 450 and 545 nm, respectively). The threshold for the spectral intensity ratio R610/R450 and R610/R545 can also be used as a marker to correlate with the new and original squamous columnar junction (SCJ), respectively. The pilot study highlights the use of new markers such as spectral contrast ratio (ρ) and spectral intensity ratio (R610/R450 and R610/R545) images.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Biophotonics Asunto de la revista: BIOFISICA Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Biophotonics Asunto de la revista: BIOFISICA Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Alemania