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Principles and Practices of Returning Individual Research Results to Participants in Large Studies of Pregnancy and Childhood.
Mash, Clay; McAllister, Kimberly A; Wonnum, Sundania; Vargas, Ashley J; Dowling, Gaya; Arteaga, S Sonia; Blaisdell, Carol J; Hardy, Kristina K; Das, Irene Prabhu; Raju, Tonse N K; Gillman, Matthew W.
Afiliación
  • Mash C; Environmental influences on Child Health Outcomes (ECHO) Program, Office of the Director.
  • McAllister KA; National Institute of Environmental Health Sciences.
  • Wonnum S; National Institute on Minority Health and Health Disparities.
  • Vargas AJ; Eunice Kennedy Shriver National Institute of Child Health and Human Development.
  • Dowling G; National Institute on Drug Abuse.
  • Arteaga SS; Environmental influences on Child Health Outcomes (ECHO) Program, Office of the Director.
  • Blaisdell CJ; Environmental influences on Child Health Outcomes (ECHO) Program, Office of the Director.
  • Hardy KK; National Institute of Neurological Disorders and Stroke.
  • Das IP; All of Us Research Program, Office of the Director, all at National Institutes of Health.
  • Raju TNK; Environmental influences on Child Health Outcomes (ECHO) Program, Office of the Director.
  • Gillman MW; Environmental influences on Child Health Outcomes (ECHO) Program, Office of the Director.
Am J Epidemiol ; 2024 Jul 19.
Article en En | MEDLINE | ID: mdl-39030726
ABSTRACT
Investigators conducting human subject research have typically conveyed only clinically actionable results back to individual participants. Shifting scientific culture around viewing participants as partners in research, however, is prompting investigators to consider returning as much data or results as the participant would like, even if they are not clearly actionable. Expanding return of individual results may add value for individual participants and their communities, refine future research questions and methods, build trust, and enhance retention of participants. Yet, gaps remain in understanding the implications of these changes for groups of 'vulnerable' participants, including pregnant and pediatric participants. We present the findings of a National Institutes of Health workshop on returning individual research results, particularly as applicable to pregnant and pediatric participants. Research participants who were panelists at the workshop agreed that they desire to receive their results. Workshop findings and current literature indicate that participants have differing preferences for what results they receive. One way to address the limits of current practice is to develop flexible digital platforms that convey individual results along with researchers' availability to answer questions, and to provide as much information as possible about actionable steps to control environmental exposures associated with disease risk.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Am J Epidemiol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Am J Epidemiol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos