Your browser doesn't support javascript.
loading
Generation of induced pluripotent stem cell line (XWHNi003-A) from a female with APOE gene mutation.
Gong, Jin; Li, Shaoqi; Sun, Wenxian; Wang, Pin; Han, Xiaodong; Xu, Chang; Chen, Yufei; Yang, Yuting; Luan, Heya; Li, Ruina; Wen, Boye; Lv, Sirong; Chen, Runqi; Guo, Jinxuan; Wei, Cuibai.
Afiliación
  • Gong J; College of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine, Changchun, China; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases,
  • Li S; College of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine, Changchun, China; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases,
  • Sun W; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Wang P; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Han X; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Xu C; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Chen Y; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Yang Y; School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Luan H; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Li R; School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Wen B; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Lv S; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
  • Chen R; School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Guo J; College of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine, Changchun, China.
  • Wei C; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China. Electronic address: weicb@xwhosp.org.
Stem Cell Res ; 79: 103501, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39029293
ABSTRACT
Apolipoprotein E (APOE)is the gene with greatest genetic risk for Alzheimer's disease (AD). We successfully established a human induced pluripotent stem cell(iPSC) line from a woman mutated by APOE gene. The cell line was isolated from this woman's peripheral blood mononuclear cells using a non-integrated Sendai virus, which retained the original genotype, showed a normal karyotype, highly expressed pluripotent markers and could differentiate into three germ layers.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apolipoproteínas E / Células Madre Pluripotentes Inducidas / Mutación Límite: Female / Humans Idioma: En Revista: Stem Cell Res Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apolipoproteínas E / Células Madre Pluripotentes Inducidas / Mutación Límite: Female / Humans Idioma: En Revista: Stem Cell Res Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido