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Systematic review: Global host range, case fatality and detection rates of Mycobacterium ulcerans in humans and potential environmental sources.
Tchatchouang, Serges; Andre Mbongue Mikangue, Chris; Kenmoe, Sebastien; Bowo-Ngandji, Arnol; Mahamat, Gadji; Thierry Ebogo-Belobo, Jean; Serge Mbaga, Donatien; Rodrigue Foe-Essomba, Joseph; Numfor, Hycenth; Irma Kame-Ngasse, Ginette; Nyebe, Inès; Bosco Taya-Fokou, Jean; Zemnou-Tepap, Cromwel; Félicité Yéngué, Jacqueline; Nina Magoudjou-Pekam, Jeannette; Gertrude Djukouo, Larissa; Antoinette Kenmegne Noumbissi, Marie; Kenfack-Momo, Raoul; Aimee Touangnou-Chamda, Sabine; Flore Feudjio, Alfloditte; Gael Oyono, Martin; Paola Demeni Emoh, Cynthia; Raoul Tazokong, Hervé; Zeukeng, Francis; Kengne-Ndé, Cyprien; Njouom, Richard; Flore Donkeng Donfack, Valerie; Eyangoh, Sara.
Afiliación
  • Tchatchouang S; Scientific Direction, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
  • Andre Mbongue Mikangue C; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Kenmoe S; Virology Department, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
  • Bowo-Ngandji A; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
  • Mahamat G; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Thierry Ebogo-Belobo J; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Serge Mbaga D; Medical Research Centre, Institute of Medical Research and Medicinal Plants Studies, Yaoundé, Cameroon.
  • Rodrigue Foe-Essomba J; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Numfor H; Department of Mycobacteriology, Centre Pasteur du Cameroun, Yaounde, Cameroon.
  • Irma Kame-Ngasse G; Scientific Direction, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
  • Nyebe I; Department of Mycobacteriology, Centre Pasteur du Cameroun, Yaounde, Cameroon.
  • Bosco Taya-Fokou J; Medical Research Centre, Institute of Medical Research and Medicinal Plants Studies, Yaoundé, Cameroon.
  • Zemnou-Tepap C; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Félicité Yéngué J; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Nina Magoudjou-Pekam J; Department of Biochemistry, The University of Yaounde I, Yaoundé, Cameroon.
  • Gertrude Djukouo L; Department of Animals Biology and Physiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Antoinette Kenmegne Noumbissi M; Department of Biochemistry, The University of Yaounde I, Yaoundé, Cameroon.
  • Kenfack-Momo R; Department of Biochemistry, The University of Yaounde I, Yaoundé, Cameroon.
  • Aimee Touangnou-Chamda S; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Flore Feudjio A; Department of Biochemistry, The University of Yaounde I, Yaoundé, Cameroon.
  • Gael Oyono M; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Paola Demeni Emoh C; Department of Biochemistry, The University of Yaounde I, Yaoundé, Cameroon.
  • Raoul Tazokong H; Department of Animals Biology and Physiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Zeukeng F; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Kengne-Ndé C; Department of Microbiology, The University of Yaounde I, Yaoundé, Cameroon.
  • Njouom R; Department Biochemistry and Molecular Biology, University of Buea, Buea, Cameroon.
  • Flore Donkeng Donfack V; Research Monitoring and Planning Unit, National Aids Control Committee, Douala, Cameroon.
  • Eyangoh S; Virology Department, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
J Clin Tuberc Other Mycobact Dis ; 36: 100457, 2024 Aug.
Article en En | MEDLINE | ID: mdl-39026996
ABSTRACT
Fundamental aspects of the epidemiology and ecology of Mycobacterium ulcerans (MU) infections including disease burden, host range, reservoir, intermediate hosts, vector and mode of transmission are poorly understood. Understanding the global distribution and burden of MU infections is a paramount to fight against Buruli ulcer (BU). Four databases were queried from inception through December 2023. After critical review of published resources on BU, 155 articles (645 records) published between 1987 and 2023 from 16 countries were selected for this review. Investigating BU in from old endemic and new emerging foci has allowed detection of MU in humans, animals, plants and various environmental samples with prevalence from 0 % up to 100 % depending of the study design. A case fatality rate between 0.0 % and 50 % was described from BU patients and deaths occurred in Central African Republic, Gabon, Democratic Republic of the Congo, Burkina Faso and Australia. The prevalence of MU in humans was higher in Africa. Nucleic Acid Amplification Tests (NAAT) and non-NAAT were performed in > 38 animal species. MU has been recovered in culture from possum faeces, aquatic bugs and koala. More than 7 plant species and several environmental samples have been tested positive for MU. This review provided a comprehensive set of data on the updates of geographic distribution, the burden of MU infections in humans, and the host range of MU in non-human organisms. Although MU have been found in a wide range of environmental samples, only few of these have revealed the viability of the mycobacterium and the replicative non-human reservoirs of MU remain to be explored. These findings should serve as a foundation for further research on the reservoirs, intermediate hosts and transmission routes of MU.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Tuberc Other Mycobact Dis Año: 2024 Tipo del documento: Article País de afiliación: Camerún Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Tuberc Other Mycobact Dis Año: 2024 Tipo del documento: Article País de afiliación: Camerún Pais de publicación: Reino Unido