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Unraveling the fatigue puzzle: insights into the pathogenesis and management of IBD-related fatigue including the role of the gut-brain axis.
Truyens, Marie; Lernout, Hannah; De Vos, Martine; Laukens, Debby; Lobaton, Triana.
Afiliación
  • Truyens M; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Lernout H; Department of Gastroenterology, University Hospital Ghent, Ghent, Belgium.
  • De Vos M; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Laukens D; VIB Center for Inflammation Research (IRC), Ghent University, Ghent, Belgium.
  • Lobaton T; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Front Med (Lausanne) ; 11: 1424926, 2024.
Article en En | MEDLINE | ID: mdl-39021817
ABSTRACT
A significant percentage of patients with an inflammatory bowel disease (IBD) encounter fatigue which can profoundly diminish patients' quality of life, particularly during periods of disease remission when gastrointestinal symptoms have receded. Various contributing risk factors have been identified including active inflammation, anemia, psychological, lifestyle and drug-related factors. While addressing these risk factors has been suggested as the initial approach to managing fatigue, a considerable number of patients still experience persisting symptoms, the primary causes of which remain incompletely understood. Recent insights suggest that dysfunction of the gut-brain axis may play a pathogenic role. This review provides an overview of established risk factors for fatigue, alongside emerging perspectives on the role of the gut-brain axis, and potential treatment strategies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Med (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Med (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Suiza