Your browser doesn't support javascript.
loading
Occurrence and potential hazard posed by pharmaceutically active compounds in coastal waters in Cape Town, South Africa.
Newman, Brent Kenneth; Velayudan, Anisha; Petrovic, Mira; Álvarez-Muñoz, Diana; Celic, Mira; Oelofse, Gregg; Colenbrander, Darryl; le Roux, Maria; Ndungu, Kuria; Madikizela, Lawrence Mzukisi; Chimuka, Luke; Richards, Heidi.
Afiliación
  • Newman BK; Coastal Systems and Earth Observation Research Group, Council for Scientific and Industrial Research (CSIR), Postnet Suite 367, Private Bag X10, Musgrave Road, Durban 4062, South Africa.; Nelson Mandela University, P.O. Box 77000, Port Elizabeth 6031, South Africa. Electronic address: Bnewman@csir.c
  • Velayudan A; Coastal Systems and Earth Observation Research Group, Council for Scientific and Industrial Research (CSIR), Postnet Suite 367, Private Bag X10, Musgrave Road, Durban 4062, South Africa.
  • Petrovic M; Catalan Institute for Water Research (ICRA)-CERCA, C/Emili Grahit 101, 17003 Girona, Spain; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
  • Álvarez-Muñoz D; Catalan Institute for Water Research (ICRA)-CERCA, C/Emili Grahit 101, 17003 Girona, Spain; University of Girona, Girona, Spain.
  • Celic M; Catalan Institute for Water Research (ICRA)-CERCA, C/Emili Grahit 101, 17003 Girona, Spain; University of Girona, Girona, Spain.
  • Oelofse G; Environmental Management Department, Coastal Management Branch, P.O. Box 16548, Vlaeberg, Cape Town 8018, South Africa.
  • Colenbrander D; Environmental Management Department, Coastal Management Branch, P.O. Box 16548, Vlaeberg, Cape Town 8018, South Africa.
  • le Roux M; Environmental Management Department, Coastal Management Branch, P.O. Box 16548, Vlaeberg, Cape Town 8018, South Africa.
  • Ndungu K; Norwegian Institute for Water Research (NIVA), Gaustadalleen 21, 0349 Oslo, Norway.
  • Madikizela LM; Institute for Nanotechnology and Water Sustainability, College of Science, Engineering and Technology, University of South Africa, Florida Science Campus, 1710, South Africa.
  • Chimuka L; Molecular Sciences Institute, School of Chemistry, University of Witwatersrand, Private Bag X3, Johannesburg 2050, South Africa.
  • Richards H; Molecular Sciences Institute, School of Chemistry, University of Witwatersrand, Private Bag X3, Johannesburg 2050, South Africa.
Sci Total Environ ; 949: 174800, 2024 Nov 01.
Article en En | MEDLINE | ID: mdl-39009155
ABSTRACT
The occurrence of 58 pharmaceutically active compounds (PhACs) in surface water at 28 coastal and five river sites, and in two stormwater flows in Cape Town, South Africa, was investigated in winter and summer. After accounting for quality assurance and control data, 33 PhACs were considered in detail. In winter, 25 PhACs were found at one or more sites and 27 in summer. Salicylic acid was the most widespread PhAC in each season. At least one PhAC was found at each site in each survey. The largest number found at a site was 22 at Lifebox23 Beach in winter and 23 at Macassar Beach and in the Black and Diep Rivers in summer. These sites are strongly directly or indirectly affected by wastewater treatment plant discharges. The range in ΣPhAC concentrations was 41 ng L-1 to 9.3 µg L-1 in winter and 109 ng L-1 to 18.9 µg L-1 in summer. The hazard posed by PhACs was estimated using Predicted No Effect Concentrations (PNEC) from several sources. Hazard Quotients (HQs) for numerous PhACs were >1, and for several even >10, including azithromycin, cimetidine, clarithromycin, erythromycin, and ibuprofen. The highest hazards were at coastal sites strongly indirectly affected by wastewater treatment plant discharges. Azithromycin, trimethoprim, and sulfamethoxazole at some sites may have promoted antibiotic resistance in bacteria, while irbesartan at some sites might have posed a hazard to fish according to the fish plasma model. The concentrations of several PhACs at some coastal sites are higher than concentrations reported in estuarine, coastal, and marine waters in other parts of the world.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminantes Químicos del Agua / Monitoreo del Ambiente País/Región como asunto: Africa Idioma: En Revista: Sci Total Environ Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminantes Químicos del Agua / Monitoreo del Ambiente País/Región como asunto: Africa Idioma: En Revista: Sci Total Environ Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos