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Pyoderma Gangrenosum Post-Breast Surgery: A Case Report and Comprehensive Review of Management Strategies.
Pop, Ioan Constantin; Ilies, Radu Alexandru; Baican, Corina; Strilciuc, Stefan; Muntean, Valentin; Muntean, Maximilian.
Afiliación
  • Pop IC; Plastic Surgery Department, "Prof. Dr. I Chiricuta" Institute of Oncology, 400015 Cluj-Napoca, Romania.
  • Ilies RA; Plastic Surgery Department, "Prof. Dr. I Chiricuta" Institute of Oncology, 400015 Cluj-Napoca, Romania.
  • Baican C; Dermatology Department, County Emergency Hospital, 400006 Cluj-Napoca, Romania.
  • Strilciuc S; Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
  • Muntean V; RoNeuro Institute for Neurological Research and Diagnostic, 400337 Cluj-Napoca, Romania.
  • Muntean M; General Surgery Department, Humanitas Clinical Hospital, 400012 Cluj-Napoca, Romania.
J Clin Med ; 13(13)2024 Jun 28.
Article en En | MEDLINE | ID: mdl-38999365
ABSTRACT
Background/

Objectives:

Pyoderma gangrenosum (PG) is a rare, autoimmune skin condition characterized by painful, rapidly progressing ulcers, often associated with autoimmune dysregulation. Managing PG following breast surgery presents unique challenges due to its pathergy phenomenon, which complicates surgical interventions. This article outlines the case of PG in a 48-year-old female post-breast surgery and reviews management strategies through a systematic analysis of the literature.

Methods:

A systematic literature review from 2018 to 2023 identified 24 relevant articles on PG management post-breast surgery. The studies were analyzed to compare the efficacy and complications of conservative versus combined (conservative and surgical) treatment strategies.

Results:

Results indicate that while conservative management, primarily with corticosteroids, remains preferred, combined strategies, including systemic therapies, vacuum-assisted closure, and surgery, offer significant benefits in select cases.

Conclusions:

Our findings suggest that a personalized, multifaceted treatment plan is crucial for managing PG effectively, emphasizing the need for early detection, meticulous planning, and comprehensive care to optimize patient outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza