Your browser doesn't support javascript.
loading
Older Adults with Cancer and Common Comorbidities-Challenges and Opportunities in Improving Their Cancer Treatment Outcomes.
Chen, Weiwei; Altshuler, Rachel D; Daschner, Phil; Salvador Morales, Carolina; St Germain, Diane C; Guida, Jennifer; Prasanna, Pataje G S; Buchsbaum, Jeffrey C.
Afiliación
  • Chen W; Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland, USA.
  • Altshuler RD; Breast and Gynecologic Cancer Research Group, Division of Cancer, National Cancer Institute, Rockville, Maryland, USA Prevention.
  • Daschner P; Cancer Immunology, Hematology, and Etiology Branch, Division of Cancer Biology, National Cancer Institute, Rockville, Maryland, USA.
  • Salvador Morales C; Nanodelivery Systems and Devices Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland, USA.
  • St Germain DC; Kelly Government Solutions, Rockville, Maryland, USA.
  • Guida J; Basic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland, USA.
  • Prasanna PGS; Radiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland, USA.
  • Buchsbaum JC; Radiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland, USA.
J Natl Cancer Inst ; 2024 Jul 12.
Article en En | MEDLINE | ID: mdl-38995839
ABSTRACT
The older American population is rapidly increasing, and millions of older adults will be cancer survivors with comorbidities. This population faces specific challenges regarding treatment and has unique clinical needs. Recognizing this need, the National Cancer Institute (NCI), in collaboration with the National Institute on Aging (NIA), hosted a webinar series, entitled "Cancer, Aging, and Comorbidities." This commentary provides a reflection of five thematic areas covered by the webinar series, which was focused on improving cancer treatment for older adults with cancer and comorbidities i) the impact of comorbidities on treatment tolerability and patient outcomes; ii) the impact of comorbidities on cancer clinical trial design; iii) the development of wearable devices in measuring comorbidities in cancer treatment; iv) the effects of nutrition and the microbiome on cancer therapy and; v) the role of senescence and senotherapy in age-related diseases. While advances have been made in these areas, many gaps and challenges exist and are discussed in this commentary. To improve cancer survivorship in older populations with comorbidities, aging and comorbidities must be jointly considered and incorporated across the spectrum of cancer research. This includes more basic research of the mechanisms linking comorbidities and cancer development and treatment response, building critical resources and infrastructure (eg, preclinical models and patient samples), conducting clinical trials focused on the older population, integrating geriatric assessment into cancer treatment, and incorporating novel technologies, such as wearable devices into clinical trials and cancer care.
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Natl Cancer Inst Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Natl Cancer Inst Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos