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Why are continent catheterizable channels continent? A stomal pressure profilometry feasibility study.
Christiaans, Coen H H; Polm, Pepijn D; van Steenbergen, Thomas R F; Wyndaele, Michel I A; de Kort, Laetitia M O.
Afiliación
  • Christiaans CHH; Department of Urology, UMC Utrecht, Utrecht, The Netherlands.
  • Polm PD; Department of Urology, UMC Utrecht, Utrecht, The Netherlands.
  • van Steenbergen TRF; Department of Urology, UMC Utrecht, Utrecht, The Netherlands.
  • Wyndaele MIA; Department of Urology, UMC Utrecht, Utrecht, The Netherlands.
  • de Kort LMO; Department of Urology, UMC Utrecht, Utrecht, The Netherlands.
Neurourol Urodyn ; 43(8): 2093-2100, 2024 Nov.
Article en En | MEDLINE | ID: mdl-38989648
ABSTRACT

INTRODUCTION:

A continent catheterizable channel (CCC) may be a solution for patients with impaired bladder emptying and difficult transurethral access. Leakage of the CCC is a common complication. To prevent leakage, the pressure in the CCC has to be higher than the reservoir (bladder/pouch) pressure in at least one location. It has not been clearly defined through which mechanism(s) the CCC achieves continence. In this feasibility study, we measured the CCC pressure profile in adult patients with various types of CCC's with and without stomal leakage.

METHODS:

Adult patients with a CCC on a (augmented) bladder or pouch who underwent a urodynamic investigation between January and March 2023 were included. Next to the standard urodynamic investigation, a continuous stomal pressure measurement (CSP) and stomal pressure profilometry with empty bladder (SPP-1) and with filled bladder (SPP-2) of the CCC were performed.

RESULTS:

A total of 17 patients were included. It was technically possible to perform SPP-1 and SPP-2 in all patients, and to measure the CSP in 16/17 patients. The median maximum stomal pressures in SPP-1 and SPP-2 were 112 (interquartile range [IQR], 76-140) cmH2O and 120 (IQR, 92-140) cmH2O, respectively. Nine patients had stomal leakage during the urodynamic investigation. In five patients, the detrusor leak point pressure (dLPP) was low (<20 cmH2O). A pressure peak at the beginning of SPP-2 was absent in all patients with stomal leakage at low dLPP.

CONCLUSION:

SPP and CSP measurement in CCCs are feasible. We found differences in SPP-2 between patients with and without leakage at low dLPP, indicative of a role of the intravesical tunnel in continence or high dLPP. The results of this study may improve our understanding of the physiology and dynamics of CCCs as well as the management of CCC-related complications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión / Urodinámica / Cateterismo Urinario / Estudios de Factibilidad Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neurourol Urodyn Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión / Urodinámica / Cateterismo Urinario / Estudios de Factibilidad Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neurourol Urodyn Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos