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Efficacy of dupilumab in the treatment of severe vulvar pruritus associated with lichen sclerosus et atrophicus: a case report.
Du, Na; Mao, Qiuyu; Yang, Jingyi; Zhang, Yiwen; Lyu, Xinyan; Li, Yueyue; Min, Wei; Xu, Jing.
Afiliación
  • Du N; Department of Dermatology and Venereology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Mao Q; Minhang Hospital, Fudan University, Shanghai, China.
  • Yang J; Department of Dermatology and Venereology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Zhang Y; Department of Dermatology and Venereology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Lyu X; Department of Dermatology and Venereology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Li Y; Department of Dermatology and Venereology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Min W; Department of Dermatology and Venereology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Xu J; Department of Dermatology and Venereology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, China.
Front Med (Lausanne) ; 11: 1422389, 2024.
Article en En | MEDLINE | ID: mdl-38988357
ABSTRACT
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory skin lesion with an undefined cause. It is more commonly found in the genital area, particularly in adolescents, premenopausal women and postmenopausal women. LSA is difficult to treat and often recurs. The primary treatment for LSA involves the administration of potent topical corticosteroids. Dupilumab is increasingly being used for the treatment of itching in non-atopic dermatitis patients but there are few reports on its use for the treatment of LSA. Here, we present a case of LSA in a 61-year-old woman with extensive vulvar itching. Over four months of dupilumab therapy, significant therapeutic effects were observed, including vulvar skin thinning and pruritus relief without adverse reactions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Med (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Med (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza