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Biosecurity measures to control hepatitis E virus on European pig farms.
Dubbert, Tamino; Meester, Marina; Smith, Richard Piers; Tobias, Tijs J; Di Bartolo, Ilaria; Johne, Reimar; Pavoni, Enrico; Krumova-Valcheva, Gergana; Sassu, Elena Lucia; Prigge, Christopher; Aprea, Giuseppe; May, Hannah; Althof, Nadine; Ianiro, Giovanni; Zmudzki, Jacek; Dimitrova, Albena; Alborali, Giovanni Loris; D'Angelantonio, Daniela; Scattolini, Silvia; Battistelli, Noemi; Burow, Elke.
Afiliación
  • Dubbert T; Department of Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
  • Meester M; Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University (UU), Utrecht, Netherlands.
  • Smith RP; Department of Epidemiological Sciences, Animal and Plant Health Agency (APHA) - Weybridge, Surrey, United Kingdom.
  • Tobias TJ; Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University (UU), Utrecht, Netherlands.
  • Di Bartolo I; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Johne R; Department of Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
  • Pavoni E; Food Safety Department, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna (IZSLER), Brescia, Italy.
  • Krumova-Valcheva G; National Food Safety Center, National Diagnostic and Research Veterinary Medical Institute (NDRVMI), Sofia, Bulgaria.
  • Sassu EL; Institute for Veterinary Disease Control, Austrian Agency for Health and Food Safety (AGES), Mödling, Austria.
  • Prigge C; Institute for Veterinary Disease Control, Austrian Agency for Health and Food Safety (AGES), Mödling, Austria.
  • Aprea G; Department of Food Safety, Experimental Zooprophylactic Institute of Abruzzo and Molise 'G. Caporale' (IZS), Teramo, Italy.
  • May H; Department of Epidemiological Sciences, Animal and Plant Health Agency (APHA) - Weybridge, Surrey, United Kingdom.
  • Althof N; Department of Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
  • Ianiro G; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Zmudzki J; Department of Swine Diseases, National Veterinary Research Institute (PIWet), Pulawy, Poland.
  • Dimitrova A; National Food Safety Center, National Diagnostic and Research Veterinary Medical Institute (NDRVMI), Sofia, Bulgaria.
  • Alborali GL; Food Safety Department, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna (IZSLER), Brescia, Italy.
  • D'Angelantonio D; Department of Food Safety, Experimental Zooprophylactic Institute of Abruzzo and Molise 'G. Caporale' (IZS), Teramo, Italy.
  • Scattolini S; Department of Food Safety, Experimental Zooprophylactic Institute of Abruzzo and Molise 'G. Caporale' (IZS), Teramo, Italy.
  • Battistelli N; Department of Food Safety, Experimental Zooprophylactic Institute of Abruzzo and Molise 'G. Caporale' (IZS), Teramo, Italy.
  • Burow E; Department of Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
Front Vet Sci ; 11: 1328284, 2024.
Article en En | MEDLINE | ID: mdl-38983773
ABSTRACT
Hepatitis E virus (HEV) genotype 3 is a prevalent zoonotic pathogen in European pig farms, posing a significant public health risk primarily through the foodborne route. The study aimed to identify effective biosecurity measures for controlling HEV transmission on pig farms, addressing a critical gap in current knowledge. Utilizing a cross-sectional design, fecal samples from gilts, dry sows, and fatteners were collected on 231 pig farms of all farm types across nine European countries. Real-time RT-PCR was employed to test these samples for HEV. Simultaneously, a comprehensive biosecurity questionnaire captured data on various potential measures to control HEV. The dependent variable was HEV risk, categorized as lower or higher based on the percentage of positive pooled fecal samples on each farm (25% cut-off). The data were analyzed using generalized linear models (one for finisher samples and one for all samples) with a logit link function with country and farm type as a priori fixed factors. The results of the final multivariable models identified key biosecurity measures associated with lower HEV risk, which were the use of a hygienogram in the breeding (OR 0.06, p = 0.001) and/or fattening area after cleaning (OR 0.21, p = 0.019), the presence of a quarantine area (OR 0.29, p = 0.025), testing and/or treating purchased feed against Salmonella (OR 0.35, p = 0.021), the presence of other livestock species on the farm, and having five or fewer persons in charge of the pigs. Contrary to expectations, some biosecurity measures were associated with higher HEV risk, e.g., downtime of 3 days or longer after cleaning in the fattening area (OR 3.49, p = 0.005) or mandatory handwashing for farm personnel when changing barn sections (OR 3.4, p = 0.026). This novel study unveils critical insights into biosecurity measures effective in controlling HEV on European pig farms. The identification of both protective and risk-associated measures contributes to improving strategies for managing HEV and underscores the complexity of biosecurity in pig farming.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Vet Sci Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Vet Sci Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza