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Nonspecific inflammatory pseudotumor of the maxillary and temporal fossa: a study of seven cases.
Kakuguchi, Wataru; Ashikaga, Yuichi; Moritani, Yasuhito; Nakano, Shintaro; Ogawa, Naohiro; Yoshitatsu, Rieko; Yanagawa-Matsuda, Aya; Maishi, Nako; Kudo, Akihiko; Okazaki, Nanase; Nakamaru, Yuji; Yabe, Ichiro; Matsuno, Yoshihiro; Ohiro, Yoichi.
Afiliación
  • Kakuguchi W; Department of Oral and Maxillofacial Surgery, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan. Electronic address: wkakugu@den.hokudai.ac.jp.
  • Ashikaga Y; Department of Oral and Maxillofacial Surgery, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
  • Moritani Y; Department of Oral and Maxillofacial Surgery, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan; Department of Dentistry and Oral Surgery, Sapporo City General hospital, Sapporo, Japan.
  • Nakano S; Department of Oral and Maxillofacial Surgery, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
  • Ogawa N; Department of Oral and Maxillofacial Surgery, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan; Department of Dentistry and Oral Surgery, Azabu Kitami Triology Hospital, Kitami, Japan.
  • Yoshitatsu R; Department of Oral and Maxillofacial Surgery, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
  • Yanagawa-Matsuda A; Department of Vascular Biology and Molecular Pathology, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
  • Maishi N; Department of Vascular Biology and Molecular Pathology, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
  • Kudo A; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Okazaki N; Depaetment of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan.
  • Nakamaru Y; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Yabe I; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Matsuno Y; Depaetment of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan.
  • Ohiro Y; Department of Oral and Maxillofacial Surgery, Division of Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol ; 138(4): 494-501, 2024 10.
Article en En | MEDLINE | ID: mdl-38981814
ABSTRACT

OBJECTIVE:

Inflammatory pseudotumor (IPT) is a rare, locally aggressive, benign neoplasm of unknown etiology. Because of its aggressive clinical behavior and locally destructive or infiltrative features, it may be mistaken for a malignant tumor. Approximately 5%-44% of extrapulmonary IPT occur in the head and neck, primarily affecting the orbit. STUDY

DESIGN:

Between 2008 and 2021, our hospital received referrals for seven patients (three men and four women, aged 42-73 years) with pain, swelling, mass, and trismus. Computed tomography, magnetic resonance imaging, and biopsy were performed on all patients to diagnose IPT.

RESULTS:

Of the seven patients, four received low-dose prednisolone (PSL), one underwent surgery, and two were left untreated. The IPT disappeared in one of the two untreated cases, whereas it improved and later deteriorated in the other. The surgical patient had no recurrence. Low-dose PSL was effective in two patients; however, high-dose PSL and immunosuppressants were required in the remaining two cases owing to infiltration into each orbit or brain region.

CONCLUSIONS:

Low-dose PSL treatment was applicable in IPT cases affecting the maxillary to temporal fossa region, wherein symptoms did not improve without treatment. However, when low-dose PSL was ineffective, high-dose PSL and immunosuppressants were required.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Tomografía Computarizada por Rayos X / Granuloma de Células Plasmáticas Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Tomografía Computarizada por Rayos X / Granuloma de Células Plasmáticas Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos