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Changes in serum lipids following consumption of coconut oil and palm olein oil: A sequential feeding crossover clinical trial.
Swarnamali, Hasinthi; Ranasinghe, Priyanga; Jayawardena, Ranil.
Afiliación
  • Swarnamali H; Health and Wellness Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka. Electronic address: shasinthi@yahoo.com.
  • Ranasinghe P; Department of Pharmacology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka; University/British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK.
  • Jayawardena R; Department of Physiology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Diabetes Metab Syndr ; 18(6): 103070, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38981164
ABSTRACT

BACKGROUND:

High incidence of cardiovascular disease (CVD) in South Asia is linked to genetic predisposition and diets high in saturated fatty acids (SFAs). Increased CVD prevalence correlates with rising palm oil consumption in some South Asian countries, where coconut oil and palm olein oil are primary SFA sources.

OBJECTIVE:

Compare the effects of coconut oil and palm olein oil on serum lipoprotein lipids and biochemical parameters in healthy adults.

METHODS:

A sequential feeding crossover clinical trial with two feeding periods of 8 weeks each was conducted among 40 healthy adults. Participants were provided palm olein oil in the first feeding period followed by coconut oil with a 16-week washout period in between. The outcomes measured were the difference in serum low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C), TC/HDL-C ratio, triglycerides (TG), very-low-density lipoprotein cholesterol (VLDL-C), fasting plasma glucose (FPG), and liver enzymes.

RESULTS:

Thirty-seven participants completed the study. LDL-C decreased by 13.0 % with palm olein oil (p < 0.001) and increased by 5.6 % with coconut oil (p = 0.044), showing a significant difference (p < 0.001). TC decreased by 9.9 % with palm olein oil (p < 0.001) and increased by 4.0 % with coconut oil (p = 0.044).

CONCLUSION:

Palm olein oil consumption resulted in more favorable changes in lipid-related CVD risk factors (TC, LDL-C, TCHDL-C, and FPG) compared to coconut oil. Clinical Trial Registry number and website where it was obtained (SLCTR/2019/034); https//slctr.lk/trials/slctr-2019-034.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceite de Palma / Estudios Cruzados / Aceite de Coco Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Metab Syndr Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceite de Palma / Estudios Cruzados / Aceite de Coco Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Metab Syndr Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos