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Engineering biomaterials by inkjet printing of hydrogels with functional particulates.
Cheng, Cih; Williamson, Eric J; Chiu, George T-C; Han, Bumsoo.
Afiliación
  • Cheng C; School of Mechanical Engineering, Purdue University, West Lafayette, IN USA.
  • Williamson EJ; School of Mechanical Engineering, Purdue University, West Lafayette, IN USA.
  • Chiu GT; School of Mechanical Engineering, Purdue University, West Lafayette, IN USA.
  • Han B; School of Mechanical Engineering, Purdue University, West Lafayette, IN USA.
Med X ; 2(1): 9, 2024.
Article en En | MEDLINE | ID: mdl-38975024
ABSTRACT
Hydrogels with particulates, including proteins, drugs, nanoparticles, and cells, enable the development of new and innovative biomaterials. Precise control of the spatial distribution of these particulates is crucial to produce advanced biomaterials. Thus, there is a high demand for manufacturing methods for particle-laden hydrogels. In this context, 3D printing of hydrogels is emerging as a promising method to create numerous innovative biomaterials. Among the 3D printing methods, inkjet printing, so-called drop-on-demand (DOD) printing, stands out for its ability to construct biomaterials with superior spatial resolutions. However, its printing processes are still designed by trial and error due to a limited understanding of the ink behavior during the printing processes. This review discusses the current understanding of transport processes and hydrogel behaviors during inkjet printing for particulate-laden hydrogels. Specifically, we review the transport processes of water and particulates within hydrogel during ink formulation, jetting, and curing. Additionally, we examine current inkjet printing applications in fabricating engineered tissues, drug delivery devices, and advanced bioelectronics components. Finally, the challenges and opportunities for next-generation inkjet printing are also discussed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Med X Año: 2024 Tipo del documento: Article Pais de publicación: Singapur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Med X Año: 2024 Tipo del documento: Article Pais de publicación: Singapur