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Biomaterials for extrusion-based bioprinting and biomedical applications.
Rossi, Arianna; Pescara, Teresa; Gambelli, Alberto Maria; Gaggia, Francesco; Asthana, Amish; Perrier, Quentin; Basta, Giuseppe; Moretti, Michele; Senin, Nicola; Rossi, Federico; Orlando, Giuseppe; Calafiore, Riccardo.
Afiliación
  • Rossi A; Smart Manufacturing Laboratory, Engineering Department, University of Perugia, Perugia, Italy.
  • Pescara T; Laboratory for Endocrine Cell Transplant and Biohybrid Organs, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Gambelli AM; Department of Civil and Environmental Engineering, University of Perugia, Perugia, Italy.
  • Gaggia F; Laboratory for Endocrine Cell Transplant and Biohybrid Organs, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Asthana A; Wake Forest School of Medicine, Winston Salem, NC, United States.
  • Perrier Q; Wake Forest School of Medicine, Winston Salem, NC, United States.
  • Basta G; Laboratory for Endocrine Cell Transplant and Biohybrid Organs, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Moretti M; Smart Manufacturing Laboratory, Engineering Department, University of Perugia, Perugia, Italy.
  • Senin N; Smart Manufacturing Laboratory, Engineering Department, University of Perugia, Perugia, Italy.
  • Rossi F; Engineering Department, University of Perugia, Perugia, Italy.
  • Orlando G; Wake Forest School of Medicine, Winston Salem, NC, United States.
  • Calafiore R; Diabetes Research Foundation, Confindustria Umbria, Perugia, Italy.
Front Bioeng Biotechnol ; 12: 1393641, 2024.
Article en En | MEDLINE | ID: mdl-38974655
ABSTRACT
Amongst the range of bioprinting technologies currently available, bioprinting by material extrusion is gaining increasing popularity due to accessibility, low cost, and the absence of energy sources, such as lasers, which may significantly damage the cells. New applications of extrusion-based bioprinting are systematically emerging in the biomedical field in relation to tissue and organ fabrication. Extrusion-based bioprinting presents a series of specific challenges in relation to achievable resolutions, accuracy and speed. Resolution and accuracy in particular are of paramount importance for the realization of microstructures (for example, vascularization) within tissues and organs. Another major theme of research is cell survival and functional preservation, as extruded bioinks have cells subjected to considerable shear stresses as they travel through the extrusion apparatus. Here, an overview of the main available extrusion-based printing technologies and related families of bioprinting materials (bioinks) is provided. The main challenges related to achieving resolution and accuracy whilst assuring cell viability and function are discussed in relation to specific application contexts in the field of tissue and organ fabrication.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Bioeng Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Bioeng Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza