Polyethylene Glycol-Fusion Repair of Peripheral Nerve Injuries.

Bittner, George D; Tuffaha, Sami; Shores, Jaimie T

Bittner, George D; Tuffaha, Sami; Shores, Jaimie T.

Afiliación

Bittner GD; Neuroscience Department, Patterson Laboratories, The University of Texas at Austin, Room 321, 2415 Speedway, Austin, TX 78712, USA. Electronic address: bittner@austin.utexas.edu.
Tuffaha S; Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Shores JT; Plastic & Reconstructive Surgery, Johns Hopkins University School of Medicine, 4940 Eastern Avenue, Suite A513, Baltimore, MD 21224, USA.

Hand Clin ; 40(3): 389-397, 2024 08.

Article en En | MEDLINE | ID: mdl-38972683

ABSTRACT

ABSTRACT

Axons successfully repaired with polyethylene glycol (PEG) fusion tecnology restored axonal continuity thereby preventing their Wallerian degeneration and minimizing muscle atrophy. PEG fusion studies in animal models and preliminary clinical trials involving patients with digital nerve repair have shown promise for this therapeutic approach. PEG fusion is safe to perform, and given the enormous potential benefits, there is no reason not to explore its therapeutic potential.

Asunto(s)

Traumatismos de los Nervios Periféricos; Polietilenglicoles; Humanos; Polietilenglicoles/uso terapéutico; Polietilenglicoles/administración & dosificación; Traumatismos de los Nervios Periféricos/cirugía; Animales; Regeneración Nerviosa

Palabras clave

Axonal injury; PEG-fusion; Peripheral nerve injury; Wallerian degeneration

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polietilenglicoles / Traumatismos de los Nervios Periféricos Límite: Animals / Humans Idioma: En Revista: Hand Clin Asunto de la revista: ORTOPEDIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

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