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The predictive value of estimated pulse wave velocity (ePWV) combined with BMI for newly diagnosed diabetes.
Dong, Da Bao; Qiao, Xiao Li; Chen, Cheng Wen; Bao, Wei; Chen, Chun Wei; Yuan, Xiang; Zhang, Ying.
Afiliación
  • Dong DB; Department of Nephrology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
  • Qiao XL; Department of Critical Care Medicine, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, China.
  • Chen CW; Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
  • Bao W; Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
  • Chen CW; Department of Cardiology, Xuzhou Central Hospital, Xuzhou, Jiangsu, China.
  • Yuan X; Department of Emergency Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
  • Zhang Y; Department of Nephrology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Rev Clin Esp (Barc) ; 224(8): 503-509, 2024 10.
Article en En | MEDLINE | ID: mdl-38972634
ABSTRACT

PURPOSE:

Estimated pulse wave velocity (ePWV) and body mass index (BMI) are significant predictors of new-onset diabetes. This study aims to evaluate the impact and predictive value of combining ePWV and BMI on the incidence of new-onset diabetes.

METHODS:

A secondary analysis was conducted on a cohort study by Rich Healthcare (China), involving 211,833 eligible participants. Logistic regression analysis identified factors influencing diabetes occurrence, while ROC curve analysis assessed the predictive value of ePWV, BMI, and their combination for new-onset diabetes.

RESULTS:

Over a mean follow-up period of 3.12 years, 3,000 men (1.41%) and 1,174 women (0.55%) were diagnosed with diabetes. Logistic regression revealed that BMI, triglycerides, alanine aminotransferase, blood urea nitrogen, creatinine clearance rate, ePWV, and family history of diabetes are high-risk factors for new-onset diabetes. The combination of ePWV and BMI provided a higher area under the ROC curve (0.822) compared to ePWV or BMI alone.

CONCLUSION:

Elevated levels of ePWV and BMI are independent risk factors for new-onset diabetes. Combining these measures enhances predictive accuracy compared to using either indicator alone.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Masa Corporal / Valor Predictivo de las Pruebas / Análisis de la Onda del Pulso Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Rev Clin Esp (Barc) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: España
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Masa Corporal / Valor Predictivo de las Pruebas / Análisis de la Onda del Pulso Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Rev Clin Esp (Barc) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: España