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[Role of neuromuscular blocking agents in the development of polyneuropathy and myopathy in critically ill patients]. / Rol de los bloqueantes neuromusculares en el desarrollo de polineuropatía y miopatía del enfermo crítico.
Armestar, Fernando; Vitoria Rubio, Sara; Ojanguren Sabán, Isabel; Coll-Cantí, Jaume; Perez Molto, Hipólito.
Afiliación
  • Armestar F; Servicio de Medicina Intensiva, Hospital Universitario Germans Trias i Pujol, Barcelona, España; Departamento de Medicina, Universidad Autónoma de Barcelona, Barcelona, España. Electronic address: farmestar.germanstrias@gencat.cat.
  • Vitoria Rubio S; Servicio de Medicina Intensiva, Hospital Universitario Germans Trias i Pujol, Barcelona, España.
  • Ojanguren Sabán I; Servicio de Anatomía Patológica, Hospital Universitario Germans Trias i Pujol, Barcelona, España.
  • Coll-Cantí J; Unidad Patología Neuromuscular, Departamento Neurociencias, Hospital Universitario Germans Trias i Pujol, Barcelona, España.
  • Perez Molto H; Servicio de Medicina Intensiva, Hospital Universitario Germans Trias i Pujol, Barcelona, España.
Med Clin (Barc) ; 163(7): 323-326, 2024 10 18.
Article en En, Es | MEDLINE | ID: mdl-38960793
ABSTRACT

BACKGROUND:

Acquired critical illness weakness (AWCIP) is the most frequent neuromuscular disease in intensive care medicine departments. Its importance is given by the prolongation of hospital stay and the delayed recovery it causes to patients after hospitalization. The main objective of this study was to investigate the association between neuromuscular blocking agents and the development of acquired weakness in critically ill patients. MATERIAL AND

METHODS:

We conducted a prospective study of 103 critically ill patients who were periodically monitored with electromyography.

RESULTS:

The development of AWCIP was observed in 63 patients. The group of patients who developed AWCIP had a significantly higher utilization of neuromuscular blocking agents than the group who did not develop AWCIP [79.4% vs 50%, OR3.85 (1.63-9.39), p <0.02]; likewise, this group of patients had a longer ICU stay [32 days vs 14 days, OR 1.11 (1.06-1.17), p <0. 001] and a longer mechanical ventilation time [24 days vs 9 days, OR1.2 (1.11-1.32), p <0.001].

CONCLUSION:

Neuromuscular blocking agents are a factor associated with the occurrence of AWCIP.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polineuropatías / Enfermedad Crítica / Electromiografía / Enfermedades Musculares / Bloqueantes Neuromusculares Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Med Clin (Barc) Año: 2024 Tipo del documento: Article Pais de publicación: España

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polineuropatías / Enfermedad Crítica / Electromiografía / Enfermedades Musculares / Bloqueantes Neuromusculares Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Med Clin (Barc) Año: 2024 Tipo del documento: Article Pais de publicación: España