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Global Trends and Frontier in Research on Pancreatic Alpha Cells: A Bibliometric Analysis from 2013 to 2023.
Guo, Teng; Zhang, Haoling; Luo, Yunpeng; Yang, Xi; Wang, Lidan; Zhang, Guangde.
Afiliación
  • Guo T; Department of Endocrinology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Zhang H; Graduate School, Beijing University of Chinese Medicine, Beijing, China.
  • Luo Y; Institute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Yang X; Department of Endocrinology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Wang L; Graduate School, Beijing University of Chinese Medicine, Beijing, China.
  • Zhang G; Department of Endocrinology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Clin Invest Med ; 47(2): 23-39, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38958477
ABSTRACT

PURPOSE:

Over the past 20 years, much of the research on diabetes has focused on pancreatic beta cells. In the last 10 years, interest in the important role of pancreatic alpha cells in the pathogenesis of diabetes, which had previously received little attention, has grown. We aimed to summarize and visualize the hotspot and development trends of pancreatic alpha cells through bibliometric analysis and to provide research direction and future ideas for the treatment of diabetes and other islet-related diseases.

METHODS:

We used two scientometric software packages (CiteSpace 6.1.R6 and VOSviewer1.6.18) to visualize the information and connection of countries, institutions, authors, and keywords in this field.

RESULTS:

A total of 532 publications, published in 752 institutions in 46 countries and regions, were included in this analysis. The United States showed the highest output, accounting for 39.3% of the total number of published papers. The most active institution was Vanderbilt University, and the authors with highest productivity came from Ulster University. In recent years, research hotspots have concentrated on transdifferentiation, gene expression, and GLP-1 regulatory function. Visualization analysis shows that research hotspots mainly focus on clinical diseases as well as physiological and pathological mechanisms and related biochemical indicators.

CONCLUSIONS:

This study provides a review and summary of the literature on pancreatic alpha cells through bibliometric and visual methods and shows research hotspot and development trends, which can guide future directions for research.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bibliometría / Células Secretoras de Glucagón Límite: Animals / Humans Idioma: En Revista: Clin Invest Med Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Canadá
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bibliometría / Células Secretoras de Glucagón Límite: Animals / Humans Idioma: En Revista: Clin Invest Med Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Canadá