Atomic Force Microscopy for the Study of Cell Mechanics in Pharmaceutics.
Pharmaceutics
; 16(6)2024 May 29.
Article
en En
| MEDLINE
| ID: mdl-38931854
ABSTRACT
Cell mechanics is gaining attraction in drug screening, but the applicable methods have not yet become part of the standardized norm. This review presents the current state of the art for atomic force microscopy, which is the most widely available method. The field is first motivated as a new way of tracking pharmaceutical effects, followed by a basic introduction targeted at pharmacists on how to measure cellular stiffness. The review then moves on to the current state of the knowledge in terms of experimental results and supplementary methods such as fluorescence microscopy that can give relevant additional information. Finally, rheological approaches as well as the theoretical interpretations are presented before ending on additional methods and outlooks.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Pharmaceutics
Año:
2024
Tipo del documento:
Article
País de afiliación:
Austria
Pais de publicación:
Suiza