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Characterization and Management of Stable Coronary Artery Disease in Patients Undergoing Transcatheter Aortic Valve Implantation.
Sammartino, Sofia; Laterra, Giulia; Pilgrim, Thomas; Amat Santos, Ignacio J; De Backer, Ole; Kim, Won-Keun; Ribeiro, Henrique Barbosa; Saia, Francesco; Bunc, Matjaz; Tchetche, Didier; Garot, Philippe; Ribichini, Flavio Luciano; Mylotte, Darren; Burzotta, Francesco; Watanabe, Yusuke; Bedogni, Francesco; Tesorio, Tullio; Rheude, Tobias; Sardella, Gennaro; Tocci, Marco; Franzone, Anna; Valvo, Roberto; Savontaus, Mikko; Wienemann, Hendrik; Porto, Italo; Gandolfo, Caterina; Iadanza, Alessandro; Bortone, Alessandro Santo; Mach, Markus; Latib, Azeem; Biasco, Luigi; Taramasso, Maurizio; De Marco, Federico; Frittitta, Valentina; Dipietro, Elena; Reddavid, Claudia; Strazzieri, Orazio; Motta, Silvia; Comis, Alessandro; Melfa, Chiara; Calì, Mariachiara; Sgroi, Carmelo; Abdel-Wahab, Mohamed; Stefanini, Giulio; Tamburino, Corrado; Barbanti, Marco; Costa, Giuliano.
Afiliación
  • Sammartino S; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Laterra G; Ospedale Umberto I, ASP 4 di Enna, 94100 Enna, Italy.
  • Pilgrim T; Bern University Hospital, Inselspital, 3010 Bern, Switzerland.
  • Amat Santos IJ; Division of Cardiology, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, Spain.
  • De Backer O; The Heart Center, Rigshospitalet, Copenhagen University Hospital, 1165 Copenhagen, Denmark.
  • Kim WK; Kerckhoff Heart Center, 61231 Bad Nauheim, Germany.
  • Ribeiro HB; Heart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo 17012-901, Brazil.
  • Saia F; Cardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
  • Bunc M; Department of Cardiology, University Medical Centre Ljubljana, 1525 Ljubljana, Slovenia.
  • Tchetche D; Clinique Pasteur, 31300 Toulouse, France.
  • Garot P; Institut Cardiovasculaire Paris-Sud, Hôpital Jacques Cartier, Ramsay-Santé, 91300 Massy, France.
  • Ribichini FL; Division of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, 37126 Verona, Italy.
  • Mylotte D; Galway University Hospital, H91 YR71 Galway, Ireland.
  • Burzotta F; Department of Cardiology, IRCSS Policlinico Universitario "Agostino Gemelli", Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
  • Watanabe Y; Department of Cardiology, Teikyo University School of Medicine, Tokyo 173-8605, Japan.
  • Bedogni F; Division of Cardiology, IRCSS Policlinico San Donato, 20097 San Donato Milanese, Italy.
  • Tesorio T; Clinica Montevergine, GVM Care & Research, 48033 Mercogliano, Italy.
  • Rheude T; German Heart Centre, 06120 Munich, Germany.
  • Sardella G; Division of Cardiology, Policlinico Umberto I, 00185 Roma, Italy.
  • Tocci M; Division of Cardiology, Policlinico Umberto I, 00185 Roma, Italy.
  • Franzone A; Division of Cardiology, AOU Federico II, Università di Napoli, 80125 Napoli, Italy.
  • Valvo R; Division of Cardiology, IRCSS Policlinico San Donato, 20097 San Donato Milanese, Italy.
  • Savontaus M; Heart Center, Turku University Hospital, 20014 Turku, Finland.
  • Wienemann H; Faculty of Medicine, University Hospital Cologne, Clinic III for Internal Medicine, University of Cologne, 50923 Cologne, Germany.
  • Porto I; CardioThoracic and Vascular Department, San Martino Policlinico Hospital, 16132 Genova, Italy.
  • Gandolfo C; Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT), 90127 Palermo, Italy.
  • Iadanza A; Azienda Ospedaliera Universitaria Senese, UOSA Cardiologia Interventistica, Policlinico Le Scotte, 53100 Siena, Italy.
  • Bortone AS; Division of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, 70124 Bari, Italy.
  • Mach M; Department of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.
  • Latib A; Montefiore Medical Center, New York, NY 10461, USA.
  • Biasco L; Azienda Sanitaria Locale di Ciriè, Chivasso e Ivrea, ASLTO4, 10034 Chivasso, Italy.
  • Taramasso M; Heart and Valve Center, University Hospital of Zurich, University of Zurich, 8006 Zurich, Switzerland.
  • De Marco F; Centro Cardiologico Monzino, 20138 Milano, Italy.
  • Frittitta V; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Dipietro E; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Reddavid C; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Strazzieri O; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Motta S; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Comis A; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Melfa C; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Calì M; Department of Cardiology, University of Catania, 95124 Catania, Italy.
  • Sgroi C; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco", 95123 Catania, Italy.
  • Abdel-Wahab M; Heart Center Leipzig, University of Leipzig, 04109 Leipzig, Germany.
  • Stefanini G; IRCCS Istituto Clinico Humanitas, 20089 Rozzano, Italy.
  • Tamburino C; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco", 95123 Catania, Italy.
  • Barbanti M; Department of Cardiology, Università degli Studi di Enna "Kore", Piazza dell'Università, 94100 Enna, Italy.
  • Costa G; Department of Cardiology, University of Catania, 95124 Catania, Italy.
J Clin Med ; 13(12)2024 Jun 14.
Article en En | MEDLINE | ID: mdl-38930026
ABSTRACT
Background/

Objectives:

To date, data regarding the characteristics and management of obstructive, stable coronary artery disease (CAD) encountered in patients undergoing transcatheter aortic valve implantation (TAVI) are sparse. The aim of the study was to analyze granular details, treatment, and outcomes of patients undergoing TAVI with obstructive, stable CAD from real-world practice.

Methods:

REVASC-TAVI (Management of myocardial REVASCularization in patients undergoing Transcatheter Aortic Valve Implantation with coronary artery disease) is an investigator-initiated, multicenter registry, which collected data from patients undergoing TAVI with obstructive stable CAD found during the pre-TAVI work-up.

Results:

A total of 2025 patients from 30 centers worldwide with complete follow-up were included in the registry. Most patients had single-vessel CAD (56.1%). An involvement of proximal coronary tracts was detected in 62.5% of cases, with 12.0% of patients having CAD in left main (LM). Most patients received percutaneous coronary intervention (PCI) (n = 1617, 79.9%), especially those with proximal CAD (90.4%). At 2 years, the rates of all-cause death [Kaplan-Meier (KM) estimates 20.1% vs. 18.8%, plog-rank = 0.86] and of the composite of all-cause death, stroke, myocardial infarction, and rehospitalization for heart failure (KM estimates 29.7% vs. 27.5%, plog-rank = 0.82) did not differ between patients undergoing PCI and those who were not.

Conclusions:

Patients undergoing TAVI with obstructive CAD more commonly had a single-vessel disease and an involvement of proximal coronary tracts. They were commonly treated with PCI, with similar outcomes compared to those treated conservatively.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza