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Isolated cerebellar stroke in a paediatric patient with typical haemolytic uraemic syndrome: a case report and literature review.
Lo Bianco, Manuela; Rinella, Sergio; D'Arco, Felice; Ioannidou, Evangelia; Kaliakatsos, Marios.
Afiliación
  • Lo Bianco M; Postgraduate Training Program in Pediatrics, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
  • Rinella S; Department of Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • D'Arco F; Department of Educational Sciences, University of Catania, Catania, Italy. sergio.rinella@hotmail.com.
  • Ioannidou E; Department of Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, University College London, London, UK. sergio.rinella@hotmail.com.
  • Kaliakatsos M; Department of Neuroradiology, Great Ormond Street Hospital for Children, London, UK.
Neuroradiology ; 2024 Jun 26.
Article en En | MEDLINE | ID: mdl-38926183
ABSTRACT
Haemolytic Uraemic Syndrome (HUS) is a rare medical condition characterised by microangiopathic haemolytic anaemia, thrombocytopenia, and acute kidney injury. Neurological complications are documented but rarely involve the cerebellum. We present a unique case of a 23-month-old male with HUS triggered by Escherichia coli-O157 (E.coli-O157) infection leading to an isolated cerebellar stroke.The patient initially presented with fever, bloody stools, and seizures. Confirmation of E.coli-O157 infection was obtained, and MRI revealed an isolated cerebellar stroke. Treatment included supportive care, anticoagulation for a right atrial thrombus, with gradual improvement observed.This case highlights the unusual occurrence of isolated cerebellar stroke in HUS patients, emphasising the importance of promptly recognizing manifestations of the central nervous system and the necessity for a multidisciplinary approach. Finally, a comprehensive literature review was conducted to identify cases of HUS patients with cerebellar involvement.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Neuroradiology Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Neuroradiology Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania