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A Case of Secondary Growth Hormone Deficiency that Developed into Cirrhosis after Several Years of Interrupted Growth Hormone Replacement Therapy.
Sueki, Ayana; Kaya, Daisuke; Nagamatsu, Shinsaku; Yamamoto, Chisa; Ohta, Kohei; Matsuo, Yuya; Nishio, Yuya; Komeda, Yusuke; Kikukawa, Shoma; Matsuura, Kyohei; Matsuo, Hideki; Uejima, Masakazu; Moriya, Kei.
Afiliación
  • Sueki A; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Kaya D; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Nagamatsu S; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Yamamoto C; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Ohta K; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Matsuo Y; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Nishio Y; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Komeda Y; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Kikukawa S; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Matsuura K; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Matsuo H; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
  • Uejima M; Department of Endocrinology and Metabolism, Nara Prefecture General Medical Center, Japan.
  • Moriya K; Department of Gastroenterology, Nara Prefecture General Medical Center, Japan.
Intern Med ; 2024 Jun 27.
Article en En | MEDLINE | ID: mdl-38925969
ABSTRACT
This case report describes a patient who received hormone replacement therapy for secondary panhypopituitarism and subsequently developed diabetes. His physician decided to discontinue growth hormone (GH) replacement, which was previously deemed contraindicated. Following the diagnosis of fatty liver, the patient began to exhibit liver damage that progressed over the ensuing years, ultimately leading to cirrhosis. Common factors linked to cirrhosis were excluded, leading to the belief that GH deficiency over several years was the primary contributor to cirrhosis. Therefore, when treating patients with GH insufficiency and diabetes, clinicians should carefully consider the potential implications of GH replacement therapy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón