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Effects of medical cannabis use on physical and psychiatric symptoms across the day among older adults.
Dvorak, Robert D; Paulson, Daniel; Dunn, Michael E; Burr, Emily K; Peterson, Roselyn; Maynard, Madison; De Leon, Ardhys N; Klaver, Samantha J; Leary, Angelina V; Hayden, Emma R; Allen, Quinn; Toth, Ethan.
Afiliación
  • Dvorak RD; The University of Central Florida, Orlando, Florida, US. Electronic address: dvorak@ucf.edu.
  • Paulson D; The University of Central Florida, Orlando, Florida, US.
  • Dunn ME; The University of Central Florida, Orlando, Florida, US.
  • Burr EK; The University of Central Florida, Orlando, Florida, US.
  • Peterson R; Brown University, Department of Behavioral and Social Sciences, Providence, Rhode Island, US.
  • Maynard M; The University of Central Florida, Orlando, Florida, US.
  • De Leon AN; The University of Central Florida, Orlando, Florida, US.
  • Klaver SJ; The University of Central Florida, Orlando, Florida, US.
  • Leary AV; The University of Central Florida, Orlando, Florida, US.
  • Hayden ER; The University of Central Florida, Orlando, Florida, US.
  • Allen Q; The University of Central Florida, Orlando, Florida, US.
  • Toth E; The University of Central Florida, Orlando, Florida, US.
Psychiatry Res ; 339: 116055, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38924900
ABSTRACT

INTRODUCTION:

Older adults are increasingly using medical cannabis (MC). It is unclear if therapeutic effects increase problematic use patterns. The current study addresses this issue by examining symptom trajectories across the day and using trajectories to predict problematic use.

METHODS:

One-hundred six older adults (age range 55-74) who endorsed medical conditions approved for treatment using MC were recruited online. Participants received six text messages/day to assess momentary symptoms for 15 days.

RESULTS:

Participants provided 5,156 momentary assessments across 1,106 use days. Symptom trajectories were examined across the day. There was a decline in all symptoms following use. Negative affect, pain, and nausea evinced momentary negative reinforcement associations with cannabis intoxication. Momentary negative reinforcement was associated with adverse cannabis outcomes. Declines in post-use trauma symptoms and momentary negative reinforcement effects for negative affect were both associated with cannabis use disorder symptoms.

DISCUSSION:

These data suggest that MC may be effective in reducing common symptom clusters. However, the negative reinforcing effect (i.e., the link between use and symptom relief at the event level) may complicate the therapeutic nature (i.e., symptom reduction). Identifying interventions to maximize benefits while minimizing costs may increase the efficacy and safety of MC in older adults.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Marihuana Medicinal Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Psychiatry Res Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Marihuana Medicinal Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Psychiatry Res Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda