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Drug-Resistant Tuberculosis Case-Finding Strategies: Scoping Review.
van Wyk, Susanna S; Nliwasa, Marriott; Lu, Fang-Wen; Lan, Chih-Chan; Seddon, James A; Hoddinott, Graeme; Viljoen, Lario; Günther, Gunar; Ruswa, Nunurai; Shah, N Sarita; Claassens, Mareli.
Afiliación
  • van Wyk SS; Centre for Evidence Based Health Care, Division of Epidemiology and Biostatistics, Department of Global Health Stellenbosch University, Cape Town, South Africa.
  • Nliwasa M; Helse Nord Tuberculosis Initiative, Kamuzu University of Health Sciences, Blantyre, Malawi.
  • Lu FW; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
  • Lan CC; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
  • Seddon JA; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Hoddinott G; Department of Infectious Disease, Imperial College London, London, United Kingdom.
  • Viljoen L; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Günther G; School of Public Health, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
  • Ruswa N; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Shah NS; Department of Pulmonary Medicine and Allergology, Inselspital, Bern University Hospital, Bern, Switzerland.
  • Claassens M; Department of Human, Biological & Translational Medical Science, School of Medicine, University of Namibia, Windhoek, Namibia.
JMIR Public Health Surveill ; 10: e46137, 2024 Jun 26.
Article en En | MEDLINE | ID: mdl-38924777
ABSTRACT

BACKGROUND:

Finding individuals with drug-resistant tuberculosis (DR-TB) is important to control the pandemic and improve patient clinical outcomes. To our knowledge, systematic reviews assessing the effectiveness, cost-effectiveness, acceptability, and feasibility of different DR-TB case-finding strategies to inform research, policy, and practice, have not been conducted and the scope of primary research is unknown.

OBJECTIVE:

We therefore assessed the available literature on DR-TB case-finding strategies.

METHODS:

We looked at systematic reviews, trials, qualitative studies, diagnostic test accuracy studies, and other primary research that sought to improve DR-TB case detection specifically. We excluded studies that included patients seeking care for tuberculosis (TB) symptoms, patients already diagnosed with TB, or were laboratory-based. We searched the academic databases of MEDLINE, Embase, The Cochrane Library, Africa-Wide Information, CINAHL (Cumulated Index to Nursing and Allied Health Literature), Epistemonikos, and PROSPERO (The International Prospective Register of Systematic Reviews) using no language or date restrictions. We screened titles, abstracts, and full-text articles in duplicate. Data extraction and analyses were carried out in Excel (Microsoft Corp).

RESULTS:

We screened 3646 titles and abstracts and 236 full-text articles. We identified 6 systematic reviews and 61 primary studies. Five reviews described the yield of contact investigation and focused on household contacts, airline contacts, comparison between drug-susceptible tuberculosis and DR-TB contacts, and concordance of DR-TB profiles between index cases and contacts. One review compared universal versus selective drug resistance testing. Primary studies described (1) 34 contact investigations, (2) 17 outbreak investigations, (3) 3 airline contact investigations, (4) 5 epidemiological analyses, (5) 1 public-private partnership program, and (6) an e-registry program. Primary studies were all descriptive and included cross-sectional and retrospective reviews of program data. No trials were identified. Data extraction from contact investigations was difficult due to incomplete reporting of relevant information.

CONCLUSIONS:

Existing descriptive reviews can be updated, but there is a dearth of knowledge on the effectiveness, cost-effectiveness, acceptability, and feasibility of DR-TB case-finding strategies to inform policy and practice. There is also a need for standardization of terminology, design, and reporting of DR-TB case-finding studies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Resistente a Múltiples Medicamentos Límite: Humans Idioma: En Revista: JMIR Public Health Surveill Año: 2024 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Canadá
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Resistente a Múltiples Medicamentos Límite: Humans Idioma: En Revista: JMIR Public Health Surveill Año: 2024 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Canadá