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Transition-Metal-Catalyzed Transformations for the Synthesis of Marine Drugs.
Parte, Lucía G; Fernández, Sergio; Sandonís, Eva; Guerra, Javier; López, Enol.
Afiliación
  • Parte LG; Department of Organic Chemistry, Science Faculty, University of Valladolid (UVa), Paseo de Belén 7, 47011 Valladolid, Spain.
  • Fernández S; Department of Chemistry, School of Physical and Chemical Sciences, Queen Mary University of London (QMUL), Mile End Road, London E1 4NS, UK.
  • Sandonís E; Department of Organic Chemistry, Science Faculty, University of Valladolid (UVa), Paseo de Belén 7, 47011 Valladolid, Spain.
  • Guerra J; Department of Organic Chemistry, Science Faculty, University of Valladolid (UVa), Paseo de Belén 7, 47011 Valladolid, Spain.
  • López E; Department of Organic Chemistry, ITAP, School of Engineering (EII), University of Valladolid (UVa), Dr Mergelina, 47002 Valladolid, Spain.
Mar Drugs ; 22(6)2024 May 29.
Article en En | MEDLINE | ID: mdl-38921564
ABSTRACT
Transition metal catalysis has contributed to the discovery of novel methodologies and the preparation of natural products, as well as new chances to increase the chemical space in drug discovery programs. In the case of marine drugs, this strategy has been used to achieve selective, sustainable and efficient transformations, which cannot be obtained otherwise. In this perspective, we aim to showcase how a variety of transition metals have provided fruitful couplings in a wide variety of marine drug-like scaffolds over the past few years, by accelerating the production of these valuable molecules.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos Biológicos / Elementos de Transición / Organismos Acuáticos Límite: Animals Idioma: En Revista: Mar Drugs Asunto de la revista: BIOLOGIA / FARMACOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos Biológicos / Elementos de Transición / Organismos Acuáticos Límite: Animals Idioma: En Revista: Mar Drugs Asunto de la revista: BIOLOGIA / FARMACOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza