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Age-specific risk factors of depression among the oldest-old - evidence from the multicenter AgeCoDe-AgeQualiDe study.
Luppa, Melanie; Pabst, Alexander; Löbner, Margrit; Mallon, Tina; Brettschneider, Christian; Hajek, André; Heser, Kathrin; Kleineidam, Luca; Weyerer, Siegfried; Werle, Jochen; Pentzek, Michael; Weeg, Dagmar; Mösch, Edelgard; Wiese, Birgitt; Oey, Anke; Wagner, Michael; Maier, Wolfgang; Scherer, Martin; König, Hans-Helmut; Riedel-Heller, Steffi G.
Afiliación
  • Luppa M; Institute of Social Medicine, Occupational Health and Public Health, Leipzig University, Leipzig, Germany.
  • Pabst A; Institute of Social Medicine, Occupational Health and Public Health, Leipzig University, Leipzig, Germany.
  • Löbner M; Institute of Social Medicine, Occupational Health and Public Health, Leipzig University, Leipzig, Germany.
  • Mallon T; Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg, Eppendorf, Germany.
  • Brettschneider C; Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg, Eppendorf, Germany.
  • Hajek A; Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg, Eppendorf, Germany.
  • Heser K; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital, Bonn, Germany.
  • Kleineidam L; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital, Bonn, Germany.
  • Weyerer S; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Werle J; Central Institute of Mental Health, Medical Faculty, Mannheim, Germany.
  • Pentzek M; Central Institute of Mental Health, Medical Faculty, Mannheim, Germany.
  • Weeg D; Institute of Family Practice (ifam), Medical Faculty, University of Duisburg, Essen, Germany.
  • Mösch E; Department of Psychiatry, Technical University of Munich, Munich, Germany.
  • Wiese B; Department of Psychiatry, Technical University of Munich, Munich, Germany.
  • Oey A; Institute of General Practice, Hannover Medical School, Hannover, Germany.
  • Wagner M; Institute of General Practice, Hannover Medical School, Hannover, Germany.
  • Maier W; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital, Bonn, Germany.
  • Scherer M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • König HH; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital, Bonn, Germany.
  • Riedel-Heller SG; Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg, Eppendorf, Germany.
Front Psychiatry ; 15: 1367225, 2024.
Article en En | MEDLINE | ID: mdl-38919640
ABSTRACT

Purpose:

The present study aimed to investigate age-group-specific incidence rates and risk factors for depressive symptoms in the highest age groups.

Methods:

Data were derived from a prospective multicenter cohort study conducted in primary care - the AgeCoDe/AgeQualiDe study. In total, 2,436 patients 75 years and older were followed from baseline to ninth follow-up. To assess depressive symptoms, the short version of the Geriatric Depression Scale (GDS-15, cutoff score 6) was used. Age-specific competing risk regressions were performed to analyze risk factors for incident depressive symptoms in different age groups (75 to 79, 80 to 84, 85+ years), taking into account the accumulated mortality.

Results:

The age-specific incidence rate of depression was 33 (95% CI 29-38), 46 (95% CI 40-52) and 63 (95% CI 45-87) per 1,000 person years for the initial age groups 75 to 79, 80 to 84 and 85+ years, respectively. In competing risk regression models, female sex, mobility as well as vision impairment, and subjective cognitive decline (SCD) were found to be risk factors for incident depression for age group 75 to 79, female sex, single/separated marital status, mobility as well as hearing impairment, and SCD for age group 80 to 84, and mobility impairment for age group 85+.

Conclusion:

Depressive symptoms in latest life are common and the incidence increases with increasing age. Modifiable and differing risk factors across the highest age groups open up the possibility of specifically tailored prevention concepts.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Psychiatry Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Psychiatry Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza