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The Best Exercise Modality and Dose to Reduce Glycosylated Hemoglobin in Patients with Type 2 Diabetes: A Systematic Review with Pairwise, Network, and Dose-Response Meta-Analyses.
Liang, Zhide; Zhang, Meng; Wang, Chuanzhi; Hao, Fengwei; Yu, Yingdanni; Tian, Shudong; Yuan, Yang.
Afiliación
  • Liang Z; School of Sports Science, Qufu Normal University, Qufu, 273165, China.
  • Zhang M; Cancer Institute of The Affiliated Hospital of Qingdao University and Qingdao Cancer Institute, No. 308 Ningxia Road, Qingdao, 266071, China.
  • Wang C; Department of Physical Education, College of Physical Education, Qingdao University, Qingdao, 266071, China.
  • Hao F; School of Exercise and Health, Shanghai University of Sport, Shanghai, 200438, China.
  • Yu Y; School of Physical Education and Sports Exercise, South China Normal University, Guangzhou, 510006, China.
  • Tian S; School of Physical Education and Sports Exercise, South China Normal University, Guangzhou, 510006, China.
  • Yuan Y; School of Physical Education, Shandong University, Jinan, 250061, China.
Sports Med ; 2024 Jun 25.
Article en En | MEDLINE | ID: mdl-38916824
ABSTRACT

BACKGROUND:

Persistently elevated glycosylated hemoglobin (HbA1c) is associated with a higher risk of long-term vascular complications.

OBJECTIVE:

We evaluated the effect of different exercise modalities and doses on HbA1c levels in patients with type 2 diabetes.

METHODS:

A systematic search for randomized controlled trials involving exercise interventions in patients with type 2 diabetes was conducted across seven electronic databases, encompassing data from their inception up to October 2023. Two independent reviewers assessed the quality of the literature. Pairwise, network, and dose-response meta-analyses using the random-effects model were conducted to analyze the effect of exercise on HbA1c levels.

RESULTS:

A total of 85 randomized controlled trials with 5535 participants were included. The network meta-analysis showed that high-intensity interval training (HIIT) has the highest ranked (MD = - 0.78% [- 8.50 mmol/mol]; 95% CrI - 1.04, - 0.51), followed by combined aerobic and resistance exercise (CE) (MD = - 0.54% [- 5.90 mmol/mol]; 95% CrI - 0.69, - 0.40), yoga (MD = - 0.45% [- 4.92 mmol/mol]; 95% CrI - 0.77, - 0.13), and continuous aerobic exercise (CAE) (MD = - 0.42% [- 4.58 mmol/mol]; 95% CrI - 0.54, - 0.30). In addition, a significant improvement in HbA1c levels can be observed when the total exercise dose reaches 840 metabolic equivalent of tasks-min/week.

CONCLUSIONS:

There was low-quality evidence that HIIT, CE, yoga, and CAE may be effective treatment modalities for improving HbA1c in patients with type 2 diabetes, and there was no significant difference in efficacy. Moreover, a non-linear dose-response relationship was found for total exercise and HbA1c levels. Future research should further investigate the specific effects of different exercise doses on HbA1c levels in patients with type 2 diabetes and provide a more personalized exercise prescription.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Sports Med Asunto de la revista: MEDICINA ESPORTIVA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Sports Med Asunto de la revista: MEDICINA ESPORTIVA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Nueva Zelanda