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Malakoplakia Involving the Maxilla: A Case Report and a Review of the Literature.
Roark, Spencer C; Bruett, Carter T; Dominger, Martin G; Freedman, Paul D; Reich, Renee F.
Afiliación
  • Roark SC; Division of Dental and Oral Medicine, New York-Presbyterian/Queens, Flushing, New York, USA. spencerroa@gmail.com.
  • Bruett CT; Division of Dental and Oral Medicine, New York-Presbyterian/Queens, Flushing, New York, USA.
  • Dominger MG; Stony Brook University Hospital, Stony Brook, NY, USA.
  • Freedman PD; Division of Dental and Oral Medicine, New York-Presbyterian/Queens, Flushing, New York, USA.
  • Reich RF; Division of Dental and Oral Medicine, New York-Presbyterian/Queens, Flushing, New York, USA.
Head Neck Pathol ; 18(1): 57, 2024 Jun 25.
Article en En | MEDLINE | ID: mdl-38916759
ABSTRACT
Malakoplakia is a rare inflammatory disorder which typically occurs in immunocompromised patients secondary to impaired bactericidal activity of macrophages. While this entity commonly arises in the genitourinary and gastrointestinal tracts, lesions of the head and neck have been reported only rarely, with oral cavity involvement reported in 3 cases. The most common presentation of head and neck malakoplakia is that of a cutaneous flesh-colored papule or nodule. This case report, however, illustrates the first time malakoplakia is identified affecting the maxilla and maxillary alveolar ridge mucosa. Histochemical and immunohistochemical stains are presented and include positivity for PAS, von Kossa stain, iron stain, and CD68 and negativity for GMS and Gram stains, indicating an inability to demonstrate microbial infection. Thus, clinicians and pathologists alike should be aware of malakoplakia as a pathologic entity when forming differential diagnoses, particularly in immunosuppressed individuals.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malacoplasia Límite: Humans Idioma: En Revista: Head Neck Pathol Asunto de la revista: NEOPLASIAS / PATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malacoplasia Límite: Humans Idioma: En Revista: Head Neck Pathol Asunto de la revista: NEOPLASIAS / PATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos