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Troponinemia in Patients With Diabetic Ketoacidosis Without Acute Coronary Syndrome.
Poojary, Indira; Khalid, Usbah; Patra, Tumpa; Giri, Junu; Al Heyasat, Ammar; Basith, Sayeda; Palasamudram Shekar, Saketh; Balachandran, Anand; Haggag, Akram.
Afiliación
  • Poojary I; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
  • Khalid U; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
  • Patra T; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
  • Giri J; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
  • Al Heyasat A; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
  • Basith S; Family Medicine, Crestwood Medical Center, Huntsville, USA.
  • Palasamudram Shekar S; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
  • Balachandran A; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
  • Haggag A; Internal Medicine, Crestwood Medical Center, Huntsville, USA.
Cureus ; 16(5): e61064, 2024 May.
Article en En | MEDLINE | ID: mdl-38915971
ABSTRACT
Ischemic myocardial injury in a diabetes mellitus (DM) patient can be a trigger or a complication of diabetic ketoacidosis (DKA). This case series examines the phenomenon of elevated troponin levels in patients with DKA in the absence of obstructive coronary artery disease. Two out of three cases showed ST-segment elevation on electrocardiogram (EKG). Despite the absence of obstructive coronary artery disease on coronary angiography, all cases exhibited troponinemia (>79 ng/dl). These elevated troponin levels and EKG changes may pose diagnostic challenges for clinicians. Alternatively, troponinemia could be due to myocardial injury caused by acidotic stress and free fatty acid utilization along with increased myocardial oxygen demand and not obstructive coronary artery pathology in every case. However, a better understanding of the complex interplay between DKA and myocardial injury needs further research.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos