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Pain modulation by oxytocin.
Kawasaki, Makoto; Sakai, Akinori; Ueta, Yoichi.
Afiliación
  • Kawasaki M; Center for Joint Arthroplasty, Hospital of University of Occupational and Environmental Health, 1-1 Iseigaoka Yahatanishi-ku, Kitakyushu City, Fukuoka 807-8555, Japan. Electronic address: k-makoto@med.uoeh-u.ac.jp.
  • Sakai A; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka Yahatanishi-ku, Kitakyushu City, Fukuoka 807-8555, Japan.
  • Ueta Y; Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka Yahatanishi-ku, Kitakyushu City, Fukuoka 807-8555, Japan.
Peptides ; 179: 171263, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38897354
ABSTRACT
Oxytocin (OXT) was discovered in 1906 as a substance that promotes the pregnancy and childbirth. It affects uterine contraction and lactation. Furthermore, as one of its physiological properties, it exerts analgesic effects. The living body has an ascending pathway that transmits pain stimuli from the periphery to the center and a descending pathway that regulates the dorsal horn neurons from the upper center downward. OXT is involved in the pain-inhibitory descending pathway and generally assumed to exert analgesic effects. In this article, we describe the pain-suppressive effects of OXT, among its many physiological effects.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor / Oxitocina Límite: Animals / Female / Humans / Pregnancy Idioma: En Revista: Peptides Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor / Oxitocina Límite: Animals / Female / Humans / Pregnancy Idioma: En Revista: Peptides Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos