Your browser doesn't support javascript.
loading
Patient-Reported Outcome Measures in Patients with and without Non-Expandable Lung Secondary to Malignant Pleural Effusion-A Single-Centre Observational Study.
Petersen, Jesper Koefod; Fjaellegaard, Katrine; Rasmussen, Daniel Bech; Alstrup, Gitte; Høegholm, Asbjørn; Sidhu, Jatinder Sing; Bhatnagar, Rahul; Clementsen, Paul Frost; Laursen, Christian B; Bodtger, Uffe.
Afiliación
  • Petersen JK; Respiratory Research Unit PLUZ, Department of Internal and Respiratory Medicine, Zealand University Hospitals, Roskilde and Næstved, 4000 Roskilde, Denmark.
  • Fjaellegaard K; Institute of Regional Health Research, University of Southern Denmark, 5000 Odense, Denmark.
  • Rasmussen DB; Respiratory Research Unit PLUZ, Department of Internal and Respiratory Medicine, Zealand University Hospitals, Roskilde and Næstved, 4000 Roskilde, Denmark.
  • Alstrup G; Institute of Regional Health Research, University of Southern Denmark, 5000 Odense, Denmark.
  • Høegholm A; Respiratory Research Unit PLUZ, Department of Internal and Respiratory Medicine, Zealand University Hospitals, Roskilde and Næstved, 4000 Roskilde, Denmark.
  • Sidhu JS; Institute of Regional Health Research, University of Southern Denmark, 5000 Odense, Denmark.
  • Bhatnagar R; Respiratory Research Unit PLUZ, Department of Internal and Respiratory Medicine, Zealand University Hospitals, Roskilde and Næstved, 4000 Roskilde, Denmark.
  • Clementsen PF; Respiratory Research Unit PLUZ, Department of Internal and Respiratory Medicine, Zealand University Hospitals, Roskilde and Næstved, 4000 Roskilde, Denmark.
  • Laursen CB; Respiratory Research Unit PLUZ, Department of Internal and Respiratory Medicine, Zealand University Hospitals, Roskilde and Næstved, 4000 Roskilde, Denmark.
  • Bodtger U; Department of Respiratory Medicine, Odense University Hospital, 2900 Hellerup, Denmark.
Diagnostics (Basel) ; 14(11)2024 Jun 03.
Article en En | MEDLINE | ID: mdl-38893702
ABSTRACT

BACKGROUND:

Malignant pleural effusion (MPE) affects up to 15% of patients with malignancy, and the prevalence is increasing. Non-expandable lung (NEL) complicates MPE in up to 30% of cases. However, it is not known if patients with malignant pleural effusion and NEL are more symptomatic in activities of daily living compared to patients with MPE with expandable lung.

METHODS:

This was an observational study on consecutively recruited patients with MPE from our pleural clinic. Before thoracentesis, patients completed patient-reported outcomes on cancer symptoms (ESAS), health-related quality of life (5Q-5D-5L), and dyspnoea scores. Following thoracentesis, patients scored dyspnoea relief and symptoms during thoracentesis. Data on focused lung ultrasound and pleural effusion biochemistry were collected. The non-expandable lung diagnosis was made by pleural experts based on radiological and clinical information.

RESULTS:

We recruited 43 patients, including 12 with NEL (28%). The NEL cohort resembled those from previous studies concerning ultrasonography, pleural fluid biochemistry, and fewer cases with high volume thoracentesis. Patients with and without NEL were comparable concerning baseline demography. The 5Q-5D-5L utility scores were 0.836 (0.691-0.906) and 0.806 (0.409-0.866), respectively, for patients with and without NEL. We observed no between-group differences in symptom burden or health-related quality of life.

CONCLUSION:

While the presence of NEL affects the clinical management of recurrent MPE, the presence of NEL seems not to affect patients' overall symptom burden in patients with MPE.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Suiza