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Understanding the Role of Female Genital Tract Microbiome in Recurrent Implantation Failure.
Lafioniatis, Anastasios; Samara, Athina A; Makaritsis, Peter K; Dafopoulos, Stefanos; Sotiriou, Sotirios; Dafopoulos, Konstantinos.
Afiliación
  • Lafioniatis A; Department of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.
  • Samara AA; Department of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.
  • Makaritsis PK; Department of Embryology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
  • Dafopoulos S; Department of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.
  • Sotiriou S; Department of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.
  • Dafopoulos K; Department of Embryology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
J Clin Med ; 13(11)2024 May 28.
Article en En | MEDLINE | ID: mdl-38892884
ABSTRACT
The realization of the role of the microbiome of the female reproductive tract in health and disease has opened numerous possibilities for the scientific examination of the intertwining role between the human host and its microbiota. The imbalance in the composition of the microbial communities of the vagina and uterus is now recognized as a risk factor for many complications in pregnancy and according to the data from numerous studies, it is possible for this imbalance to play a crucial role in creating a hostile endometrial environment, and therefore, contributing to the etiology of recurrent implantation failure. Nevertheless, our current understanding of these complicated biological phenomena is far from complete, and in the future, there needs to be a systematic and thorough investigation of the diagnosis and therapy of this condition. This will enable scientists who engage in the field of assisted reproduction technologies to accurately identify and cure women in whom dysbiosis hinders the achievement of a healthy pregnancy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Suiza