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Comparison of intra- and inter-reader agreement of abbreviated versus comprehensive MRCP for pancreatic cyst surveillance.
Huang, Chenchan; Prabhu, Vinay; Smereka, Paul; Vij, Abhinav; Anthopolos, Rebecca; Hajdu, Cristina H; Dane, Bari.
Afiliación
  • Huang C; NYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA. Chenchan.huang@nyulangone.org.
  • Prabhu V; NYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
  • Smereka P; NYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
  • Vij A; NYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
  • Anthopolos R; Biostatistics Division within Department of Population Health, NYU Grossman School of Medicine, New York, United States.
  • Hajdu CH; NYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
  • Dane B; NYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
Abdom Radiol (NY) ; 49(10): 3517-3527, 2024 Oct.
Article en En | MEDLINE | ID: mdl-38888739
ABSTRACT

OBJECTIVE:

To retrospectively compare inter- and intra-reader agreement of abbreviated MRCP (aMRCP) with comprehensive MRI (cMRCP) protocol for detection of worrisome features, high-risk stigmata, and concomitant pancreatic cancer in pancreatic cyst surveillance.

METHODS:

151 patients (104 women, mean age 69[10] years) with baseline and follow-up contrast-enhanced MRIs were included. This comprised 138 patients under cyst surveillance with 5-year follow-up showing no pancreatic ductal adenocarcinoma (PDAC), 6 with pancreatic cystic lesion-derived malignancy, and 7 with concomitant PDAC. The aMRCP protocol used four sequences (axial and coronal Half-Fourier Single-shot Turbo-spin-Echo, axial T1 fat-saturated pre-contrast, and 3D-MRCP), while cMRCP included all standard sequences, including post-contrast. Three blinded abdominal radiologists assessed baseline cyst characteristics, worrisome features, high-risk stigmata, and PDAC signs using both aMRCP and cMRCP, with a 2-week washout period. Intra- and inter-reader agreement were calculated using Fleiss' multi-rater kappa and Intra-class Correlation Coefficient (ICC). 95% confidence intervals (CI) were calculated.

RESULTS:

Cyst size, growth, and abrupt main pancreatic duct transition had strong intra- and inter-reader agreement. Intra-reader agreement was ICC = 0.93-0.99 for cyst size, ICC = 0.71-1.00 for cyst growth, and kappa = 0.83-1.00 for abrupt duct transition. Inter-reader agreement for cyst size was ICC = 0.86 (aMRCP) and ICC = 0.83 (cMRCP), and for abrupt duct transition was kappa = 0.84 (aMRCP) and kappa = 0.69 (cMRCP). Thickened cyst wall, mural nodule and cyst-duct communication demonstrated varying intra-reader agreements and poor inter-reader agreements.

CONCLUSION:

aMRCP showed high intra- and inter-reader agreement for most pancreatic cyst parameters that highly rely on T2-weighted sequences.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quiste Pancreático / Neoplasias Pancreáticas / Pancreatocolangiografía por Resonancia Magnética Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Abdom Radiol (NY) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quiste Pancreático / Neoplasias Pancreáticas / Pancreatocolangiografía por Resonancia Magnética Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Abdom Radiol (NY) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos