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Impact of SARS-CoV-2 Pandemic on Emergency Hospitalizations for Acute Respiratory Infections: The Experience of a Paediatric Tertiary Care Hospital in Italy.
Ciofi Degli Atti, Marta Luisa; Beccia, Flavia; D'Amore, Carmen; Ravà, Lucilla; Bernaschi, Paola; Russo, Cristina; Villani, Alberto; Perno, Carlo Federico; Raponi, Massimiliano.
Afiliación
  • Ciofi Degli Atti ML; Epidemiology, Clinical Pathways and Clinical Risk Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Beccia F; Epidemiology, Clinical Pathways and Clinical Risk Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • D'Amore C; University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
  • Ravà L; Epidemiology, Clinical Pathways and Clinical Risk Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Bernaschi P; Epidemiology, Clinical Pathways and Clinical Risk Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Russo C; Laboratory Medicine Clinical Area, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Villani A; Laboratory Medicine Clinical Area, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Perno CF; University-Hospital Paediatric Clinical Area, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Raponi M; Laboratory Medicine Clinical Area, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Influenza Other Respir Viruses ; 18(6): e13335, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38887843
ABSTRACT

BACKGROUND:

Acute respiratory infections (ARIs) are a major healthcare issue in children. The SARS-CoV-2 pandemic changed the epidemiology of ARIs; the aims of this study are to characterize the epidemiological trend of ARI emergency hospitalizations and virology results and to estimate the association of ARI emergency hospitalizations with respiratory viruses from January 2018 to June 2023.

METHODS:

This study was carried out in an Italian tertiary care children's hospital (Bambino Gesù Children's Hospital). The demographic and clinical information of children who accessed the Emergency Department (ED) with ARI and were hospitalized were retrospectively extracted from the electronic health records. Multivariate linear regression model was used to compare the number of ARI hospital admissions with the reported temporal trends in viruses diagnosed from respiratory samples throughout the same time period.

RESULTS:

During the study period, there were 92,140 ED visits and 10,541 hospitalizations due to ARIs, reflecting an admission rate of 11.4%. The highest proportion of hospitalizations occurred in infants ≤ 1 year of age (n = 4840, 45.9% of total admissions), with a hospitalization rate of 22.6%. Emergency hospitalizations aligned closely with the predictions made by the multivariate regression model; peaks in hospitalizations reflected Respiratory Syncytial Virus (RSV) circulation.

CONCLUSIONS:

ARI hospital urgent admissions are a relevant component of ARI disease burden in children. RSV prevention and control are crucial to limit the risk of urgent hospitalizations due to ARIs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Servicio de Urgencia en Hospital / Centros de Atención Terciaria / SARS-CoV-2 / COVID-19 / Hospitalización / Hospitales Pediátricos Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Influenza Other Respir Viruses Asunto de la revista: VIROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Servicio de Urgencia en Hospital / Centros de Atención Terciaria / SARS-CoV-2 / COVID-19 / Hospitalización / Hospitales Pediátricos Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Influenza Other Respir Viruses Asunto de la revista: VIROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido