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Comparative Evaluation of Penetration of Various Nano-sized Intra-canal Medicaments: An In Vitro Confocal Laser Scanning Microscopic Study.
Veeraiyan, Mounika; Chandhar, Chikine Yashas; Mastammanavar, Deepa; Kavya, Kantheti; Jarupula, Deepa; Sairam, Gangishetti.
Afiliación
  • Veeraiyan M; Department of Conservative Dentistry and Endodontics, ESIC Dental College and Hospital, Kalaburagi, Karnataka, India.
  • Chandhar CY; Department of Conservative Dentistry and Endodontics, SVS Dental College and Hospital, Hyderabad, Telangana, India.
  • Mastammanavar D; Department of Oral Pathology and Microbiology, Basur Multispeciality Dental Clinic, Haveri, Karnataka, India.
  • Kavya K; Department of Conservative Dentistry and Endodontics, AME's Dental College and Hospital, Raichur, Karnataka, India.
  • Jarupula D; Department of Conservative Dentistry and Endodontics, Meghana Institute of Dental Sciences, Nizamabad, Telangana, India.
  • Sairam G; Department of Conservative Dentistry and Endodontics, Meghana Institute of Dental Sciences, Nizamabad, Telangana, India.
J Pharm Bioallied Sci ; 16(Suppl 2): S1690-S1694, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38882763
ABSTRACT

Background:

To assess and contrast the depth of penetration of conventional calcium hydroxide, nanoparticle calcium hydroxide, silver nanoparticles, and combination of nanoparticle calcium hydroxide and silver nanoparticles into dentinal tubules using confocal laser scanning microscope. Materials and

Methods:

Eighty human single-rooted teeth were decoronated and instrumented up to Protaper Universal F3. Teeth were separated into four groups at random (n = 20) following chemomechanical preparation. Group 1 Control Conventional Calcium Hydroxide; Group 2 Nanoparticle Calcium Hydroxide; group 3 Silver Nanoparticles; group 4 Combination of Nanoparticle Calcium Hydroxide and Silver Nanoparticles. With the use of lentulo spirals, medications were injected into the canals, stirred up with ultrasound, and then kept at 37°C for 24 hours. A 1 mm thick slice was obtained at 5 mm from the root apex by sectioning the root perpendicular to the long axis of the tooth and then put on a glass slide to measure the depth of penetration using a confocal laser microscope. Statistical

Analysis:

To quantify the depth of penetration among the four groups, a one-way ANOVA was used and post hoc-Tukey's test was used to compare between groups.

Results:

All of the groups were statistically significant, with group 4 showing the greatest depth of penetration, followed by group 2 and group 3. In contrast, all other groups in the intergroup comparison were statistically significant (P value 0.05) aside from the comparison of group 2 to group 3.

Conclusion:

Silver nanoparticles and nanoparticle calcium hydroxide together demonstrated greater penetration than calcium hydroxide, silver nanoparticles, and nanoparticle calcium hydroxide alone.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pharm Bioallied Sci Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pharm Bioallied Sci Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India