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A Big Prospect for Hydrogel Nano-System in Glioma.
Zhang, Lu; Teng, Fei; Xin, Huajie; Xu, Wei; Wu, Wei; Yao, Chenguo; Wang, Zhiqiang.
Afiliación
  • Zhang L; Key Laboratory for Biorheological Science and Technology of Ministry of Education (Chongqing University), Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
  • Teng F; Center of Thoracic Cancer, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
  • Xin H; The State Key Laboratory of Power Transmission Equipment and System Security and New Technology, College of Electrical Engineering, Chongqing University, Chongqing, 400044, People's Republic of China.
  • Xu W; Key Laboratory for Biorheological Science and Technology of Ministry of Education (Chongqing University), Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
  • Wu W; Center of Thoracic Cancer, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
  • Yao C; Key Laboratory for Biorheological Science and Technology of Ministry of Education (Chongqing University), Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
  • Wang Z; Center of Thoracic Cancer, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
Int J Nanomedicine ; 19: 5605-5618, 2024.
Article en En | MEDLINE | ID: mdl-38882547
ABSTRACT
Patients diagnosed with glioma typically face a limited life expectancy (around 15 months on average), a bleak prognosis, and a high likelihood of recurrence. As such, glioma is recognized as a significant form of malignancy. Presently, the treatment options for glioma include traditional approaches such as surgery, chemotherapy, and radiotherapy. Regrettably, the efficacy of these treatments has been less than optimal. Nevertheless, a promising development in glioma treatment lies in the use of hydrogel nano-systems as sophisticated delivery systems. These nano-systems have demonstrated exceptional therapeutic effects in the treatment of glioma by various responsive ways, including temperature-response, pH-response, liposome-response, ROS-response, light-response, and enzyme-response. This study seeks to provide a comprehensive summary of both the therapeutic application of hydrogel nano-systems in managing glioma and the underlying immune action mechanisms.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Hidrogeles / Glioma Límite: Animals / Humans Idioma: En Revista: Int J Nanomedicine Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Hidrogeles / Glioma Límite: Animals / Humans Idioma: En Revista: Int J Nanomedicine Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda